SCHEMBL347781

SCHEMBL347781

NCC=Cc1ccccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.52
NFKB1 P19838 2/20 0.50
CDK4 P11802 1/20 0.50
CCND1 P24385 1/20 0.50
JUN P05412 1/20 0.50
NFE2L2 Q16236 1/20 0.50
CA2 P00918 7/20 0.48
CA1 P00915 1/20 0.48
CA4 P22748 1/20 0.48
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
TRIM24 O15164 1/20 0.46
TRIM33 Q9UPN9 1/20 0.46
CA12 O43570 6/20 0.45
KDM4E B2RXH2 1/20 0.45
BCHE P06276 1/20 0.44
GUSB P08236 1/20 0.44
TAAR1 Q96RJ0 1/20 0.43
CA9 Q16790 5/20 0.42
SIRT2 Q8IXJ6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12425707 1.00 TRPA1 (0.52) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL31186857 1.00 TRPA1 (0.52) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL347703 0.83 TRPA1 (0.48) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL348173 0.80 TRPA1 (0.46) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL13158791 0.80 TRPA1 (0.54) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL30528037 0.80 TRPA1 (0.54) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL229461 0.80 TRPA1 (0.54) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL4630799 0.80 TRPA1 (0.54) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL9112828 0.78 TRPA1 (0.52) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL2141776 0.78 TRPA1 (0.52) TRPA1NFKB1CDK4CCND1JUN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1664431-B1 ANTIOXIDANT FOR AN ORGANIC MATERIAL AND METHOD FOR TREATING THE SAME ZFB ZENTRUM FUER BUCHERHALTUNG (DE) 2010-08-04 EP claimed
EP-1664431-A2 ANTIOXIDANT FOR AN ORGANIC MATERIAL AND METHOD FOR TREATING THE SAME ZFB Zentrum für Bucherhaltung GmbH (DE) 2006-06-07 EP claimed
WO-2005030906-A2 ANTIOXIDANT FOR AN ORGANIC MATERIAL AND METHOD FOR TREATING THE SAME ZFB Zentrum für Bucherhaltung GmbH (DE) 2005-04-07 WO claimed
EP-4179049-B1 ENGINE OIL LUBRICANT COMPOSITIONS AND METHODS FOR MAKING SAME WITH SUPERIOR ENGINE WEAR PROTECTION AND CORROSION PROTECTION EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) 2025-03-19 EP disclosed
EP-4453152-A1 ENGINE OIL LUBRICANT COMPOSTIONS AND METHODS FOR MAKING SAME WITH SUPERIOR OIL CONSUMPTION ExxonMobil Technology and Engineering Company (US) 2024-10-30 EP disclosed
EP-4114909-B1 NON-NEWTONIAN ENGINE OIL LUBRICANT COMPOSITIONS FOR SUPERIOR FUEL ECONOMY EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) 2024-10-23 EP disclosed
US-12037562-B2 Non-newtonian engine oil lubricant compositions for superior fuel economy ExxonMobil Technology and Engineering Company (US) 2024-07-16 US disclosed
US-11697782-B2 Engine oil lubricant compositions and methods for making same with superior engine wear protection and corrosion protection ExxonMobil Technology and Engineering Company (US) 2023-07-11 US disclosed
WO-2023122405-A1 ENGINE OIL LUBRICANT COMPOSTIONS AND METHODS FOR MAKING SAME WITH SUPERIOR OIL CONSUMPTION ExxonMobil Technology and Engineering Company (US) 2023-06-29 WO disclosed
US-20230193150-A1 ENGINE OIL LUBRICANT COMPOSTIONS AND METHODS FOR MAKING SAME WITH SUPERIOR OIL CONSUMPTION ExxonMobil Technology and Engineering Company (US) 2023-06-22 US disclosed
EP-4179049-A1 ENGINE OIL LUBRICANT COMPOSITIONS AND METHODS FOR MAKING SAME WITH SUPERIOR ENGINE WEAR PROTECTION AND CORROSION PROTECTION ExxonMobil Technology and Engineering Company (US) 2023-05-17 EP disclosed
WO-2005030906-A2 ANTIOXIDANT FOR AN ORGANIC MATERIAL AND METHOD FOR TREATING THE SAME ZFB Zentrum für Bucherhaltung GmbH (DE) 2005-04-07 WO disclosed
EP-0869949-B1 BENZOXAZINE ANTIMICROBIAL AGENTS ORTHO MCNEIL PHARM INC (US) 2002-12-18 EP disclosed
US-5874436-A EFFECTIVE IN INHIBITING THE ACTION OF A BACTERIAL HISTIDINE PROTEIN KINASE; USEFUL AGAINST ANTIBIOTIC RESISTANT ORGANISMS DEMERS JAMES P (US) 1999-02-23 US disclosed
US-5854242-A Benzoxazine antimicrobial agents ORTHO PHARMACEUTICAL CORPORATION (US) 1998-12-29 US disclosed
EP-0869949-A1 BENZOXAZINE ANTIMICROBIAL AGENTS ORTHO PHARMACEUTICAL CORPORATION (US) 1998-10-14 EP disclosed
US-5773469-A Diaryl antimicrobial agents ORTHO PHARMACEUTICAL CORPORATION (US) 1998-06-30 US disclosed
US-5696117-A BACTERICIDE ORTHO PHARMACEUTICAL CORPORATION (US) 1997-12-09 US disclosed
US-5643950-A INHIBITORS OF A BACTERIAL HISTIDINE PROTEIN KINASE ORTHO PHARMACEUTICAL CORPORATION (US) 1997-07-01 US disclosed
WO-1997017333-A1 BENZOXAZINE ANTIMICROBIAL AGENTS ORTHO PHARMACEUTICAL CORPORATION (US) 1997-05-15 WO disclosed