SCHEMBL3477870

SCHEMBL3477870

Cn1ccc2cc(-c3ccc4oc(N5CCc6ncncc6C5)nc4c3)ccc21

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3477536 0.86 FAAH (0.86) FAAH
SCHEMBL3478537 0.85 FAAH (0.85) FAAH
SCHEMBL3477773 0.85 FAAH (0.85) FAAH
SCHEMBL3477873 0.83 FAAH (0.84) FAAH
SCHEMBL3476806 0.83 FAAH (0.73) FAAH
SCHEMBL3476996 0.83 FAAH (1.00) FAAH
SCHEMBL3478207 0.81 FAAH (1.00) FAAH
SCHEMBL13436690 0.81 FAAH (0.66) FAAH
SCHEMBL13436691 0.80 FAAH (0.68) FAAH
SCHEMBL3477838 0.80 FAAH (1.00) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010039186-A2 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2010-04-08 WO disclosed