Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetonitrile SCHEMBL8910586 | 1.00 | MEN1 (0.33) | MEN1KMT2ATSHRALDH1A1 | |
| Acetonitrile SCHEMBL1730351 | 0.95 | MEN1 (0.31) | MEN1KMT2A | |
| Water SCHEMBL1251556 | 0.87 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL5544690 | 0.84 | MEN1 (0.42) | MEN1KMT2A | |
| SCHEMBL7097725 | 0.84 | — | — | |
| SCHEMBL1746 | 0.84 | — | — | |
| SCHEMBL28199597 | 0.83 | ALDH1A1 (0.33) | MEN1KMT2ATSHRALDH1A1 | |
| Hydrazine SCHEMBL28180292 | 0.81 | MEN1 (0.36) | MEN1KMT2A | |
| SCHEMBL319537 | 0.81 | MEN1 (0.40) | MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL1997314 | 0.81 | MEN1 (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225005-A1 | FLT3 COMBINATION THERAPY FOR CANCER AND COMPOSITIONS THEREFOR | BIOMEA FUSION, INC. (US) | 2023-11-23 | — | — | WO | disclosed |
| CN-109562168-A | anti-CD 98 antibodies and antibody drug conjugates | 艾伯维公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-108026531-A | ANTISENSE NUCLEIC ACID | 日本新药株式会社 | 2018-05-11 | — | — | CN | disclosed |
| CN-103570683-B | Polysubstituted aminated compounds and its preparation method and application | 中国科学院上海药物研究所 | 2018-04-17 | — | — | CN | disclosed |
| CN-107531668-A | Therapeutic pyridazine compound and application thereof | 基因泰克公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-106661577-A | Antisense nucleic acid | 日本新药株式会社 | 2017-05-10 | — | — | CN | disclosed |
| CN-102548557-A | Compounds for reducing beta-amyloid production | BRISTOL MYERS SQUIBB CO | 2012-07-04 | — | — | CN | disclosed |
| WO-2010146449-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF IMIPENAM | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2010-12-23 | — | — | WO | disclosed |
| US-6204384-B1 | THROMBIN INHIBITOR; ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. | 2001-03-20 | — | — | US | disclosed |
| US-6011047-A | Substituted 3-amino-2-hydroxyphenylacetamide derivatives as enzyme inhibitors | CORVAS INTERNATIONAL INC. (US) | 2000-01-04 | — | — | US | disclosed |
| WO-1999026920-A1 | SUBSTITUTED 3-AMINO-2-HYDROXYPHENYLACETAMIDE DERIVATIVES AS ENZYME INHIBITORS (II) | CORVAS INTERNATIONAL, INC. (US) | 1999-06-03 | — | — | WO | disclosed |
| EP-0690716-A4 | OLIGONUCLEOTIDES MODIFIED TO IMPROVE STABILITY AT ACID pH | UNIV JOHNS HOPKINS (US) | 1997-05-02 | — | — | EP | disclosed |
| EP-0690716-A1 | OLIGONUCLEOTIDES MODIFIED TO IMPROVE STABILITY AT ACID pH | THE JOHNS HOPKINS UNIVERSITY (US) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994015619-A1 | OLIGONUCLEOTIDES MODIFIED TO IMPROVE STABILITY AT ACID pH | THE JOHNS HOPKINS UNIVERSITY (US) | 1994-07-21 | — | — | WO | disclosed |