SCHEMBL3477934

SCHEMBL3477934

C=Cc1ccccc1C(O)=S

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
TSHR P16473 2/20 0.40
ALOX15 P16050 2/20 0.35
AKT1 P31749 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CYP3A4 P08684 2/20 0.32
CYP1A2 P05177 1/20 0.32
GAA P10253 2/20 0.32
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
TRPA1 O75762 1/20 0.31
LMNA P02545 2/20 0.31
TAS2R38 P59533 1/20 0.31
HSD17B10 Q99714 1/20 0.31
THRB P10828 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15704573 0.81 ALDH1A1 (0.44) ALDH1A1TSHRALOX15AKT1MEN1
Benzene SCHEMBL28254104 0.79 ALDH1A1 (0.56) ALDH1A1ALOX15AKT1CYP1A2KDM4E
SCHEMBL30259301 0.79 ALDH1A1 (0.56) ALDH1A1ALOX15AKT1CYP1A2KDM4E
SCHEMBL31100 0.79 ALDH1A1 (0.56) ALDH1A1ALOX15AKT1CYP1A2KDM4E
SCHEMBL15026334 0.78 ALDH1A1 (0.45) ALDH1A1TSHRMEN1KMT2ANPC1
SCHEMBL2856375 0.77 ALDH1A1 (0.54) ALDH1A1ALOX15AKT1MEN1KMT2A
SCHEMBL347539 0.77 ALDH1A1 (0.54) ALDH1A1ALOX15AKT1MEN1KMT2A
SCHEMBL2867924 0.77 ALDH1A1 (0.54) ALDH1A1ALOX15AKT1MEN1KMT2A
Hydrochloric Acid SCHEMBL2909959 0.77 ALDH1A1 (0.54) ALDH1A1ALOX15AKT1MEN1KMT2A
SCHEMBL22171641 0.77 ALDH1A1 (0.41) ALDH1A1TSHRALOX15AKT1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010046419-A2 Use of acetolactate synthase inhibitors on cultivated plants BASF SE (DE) 2010-04-29 WO disclosed
CN-1065525-C A process of producing a monomer for a highly hard transparent resin MITSUI TOATSU CHEMICALS (JP) 2001-05-09 CN disclosed
CN-1029851-C Preparation of high-hardness transparent resin MITSUI TOATSU CHEMICALS (JP) 1995-09-27 CN disclosed
CN-1108667-A A process of producing a monomer for a highly hard transparent resin MITSUI TOATSU CHEMICALS (JP) 1995-09-20 CN disclosed
CN-1104648-A A process of producing a glazing material comprising a highly hard transparent resin MITSUI TOATSU CHEMICALS (JP) 1995-07-05 CN disclosed
CN-1104649-A A process of producing an optical lens comprising a highly hard transparent resin MITSUI TOATSU CHEMICALS (JP) 1995-07-05 CN disclosed
EP-0345748-B1 Hard transparent resins and process for the production thereof MITSUI TOATSU CHEMICALS (JP) 1995-04-26 EP disclosed
US-5166285-A Polymers for optical lenses MITSUI TOATSU CHEMICALS, INC. (JP) 1992-11-24 US disclosed
US-5104953-A HARD TRANSPARENT RESINS AND PROCESS FOR THE PRODUCTION THEREOF MITSUI TOATSU CHEMICALS, INC. (JP) 1992-04-14 US disclosed
CN-1040365-A Preparation of high-hardness transparent resin MITSUI TOATSU CHEMICALS (JP) 1990-03-14 CN disclosed
EP-0345748-A2 Hard transparent resins and process for the production thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-12-13 EP disclosed