⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11174253 | 0.97 | TSHR (0.68) | — | |
| SCHEMBL8230983 | 0.97 | TSHR (0.68) | — | |
| SCHEMBL10705530 | 0.97 | TSHR (0.68) | — | |
| SCHEMBL8414687 | 0.97 | TSHR (0.68) | — | |
| SCHEMBL10613480 | 0.97 | TSHR (0.68) | — | |
| SCHEMBL25475062 | 0.97 | TSHR (0.68) | — | |
| SCHEMBL7904756 | 0.97 | TSHR (0.68) | — | |
| SCHEMBL9728632 | 0.97 | TSHR (0.68) | — | |
| SCHEMBL21385750 | 0.97 | TSHR (0.68) | — | |
| Hydrochloric Acid SCHEMBL27927808 | 0.95 | TSHR (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225191-A | Cosmetic reducing compositions for the permanent deformation of hair based on an ester of thioglycolic acid and an N-(C2 -C4) acyl cysteamine | L'OREAL (FR) | 1993-07-06 | — | — | US | claimed |
| JP-4352712-A | — | — | None | — | — | JP | disclosed |
| CN-101331117-B | 5-lipoxygenase-activating protein (FLAP) inhibitors | AMIRA PHARMACEUTICALS INC | 2012-09-05 | — | — | CN | disclosed |
| US-20120101741-A1 | DIRECT SOLID SAMPLE ANALYTICAL TECHNOLOGY FOR DETERMINING A CONTENT AND A UNIFORMITY THEREOF IN A LYOPHILIZED KIT OF A SULFUR-CONTAINING CHELATOR WITH A STABLE COMPLEX CAPACITY FOR RADIOTECHNETIUM (TC-99M) AND RADIORHENIUM (RE-186, RE-188) | INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN (TW) | 2012-04-26 | — | — | US | disclosed |
| US-20020128213-A1 | Sixteen-membered macrolide compounds | KOSAN BIOSCIENCES, INC. | 2002-09-12 | — | — | US | disclosed |
| US-20020111317-A1 | Sixteen-membered macrolide compounds | KOSAN BIOSCIENCES, INC. | 2002-08-15 | — | — | US | disclosed |
| WO-2002032916-A2 | SIXTEEN-MEMBERED MACROLIDE COMPOUNDS | KOSAN BIOSCIENCES, INC. (US) | 2002-04-25 | — | — | WO | disclosed |
| US-5225191-A | Cosmetic reducing compositions for the permanent deformation of hair based on an ester of thioglycolic acid and an N-(C2 -C4) acyl cysteamine | L'OREAL (FR) | 1993-07-06 | — | — | US | disclosed |
| US-5225191-A | Cosmetic reducing compositions for the permanent deformation of hair based on an ester of thioglycolic acid and an N-(C2 -C4) acyl cysteamine | L'OREAL (FR) | 1993-07-06 | — | — | US | disclosed |
| US-5225191-A | Cosmetic reducing compositions for the permanent deformation of hair based on an ester of thioglycolic acid and an N-(C2 -C4) acyl cysteamine | L'OREAL (FR) | 1993-07-06 | — | — | US | disclosed |
| JP-H04352712-A | REDUCING COMPOSITION FOR COSMETIC | L'OREAL SA | 1992-12-07 | — | — | JP | disclosed |