⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409991 | 0.79 | — | — | |
| SCHEMBL7313659 | 0.76 | PDPK1 (0.39) | — | |
| SCHEMBL11778525 | 0.76 | — | — | |
| SCHEMBL11779441 | 0.74 | PDPK1 (0.38) | — | |
| SCHEMBL13211644 | 0.68 | PDPK1 (0.45) | — | |
| SCHEMBL13512899 | 0.64 | RAB9A (0.34) | — | |
| SCHEMBL11778806 | 0.62 | — | — | |
| SCHEMBL11529909 | 0.60 | — | — | |
| SCHEMBL2155849 | 0.60 | — | — | |
| SCHEMBL94902 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105412094-A | Compounds, Compositions, And Methods For Preventing Metastasis Of Cancer Cells | AKEBIA THERAPEUTICS INC | 2016-03-23 | — | — | CN | claimed |
| CN-110709424-B | Compositions and methods for cellular immunotherapy | 科济生物医药（上海）有限公司 | 2024-01-05 | — | — | CN | disclosed |
| EP-3737684-B1 | 2,4,6,7-TETRAHYDRO-PYRAZOLO[4,3-D]PYRIMIDIN-5-ONE DERIVATIVES AND RELATED COMPOUNDS AS C5A RECEPTOR MODULATORS FOR TREATING VASCULITIS AND INFLAMMATORY DISEASES | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-11-16 | — | — | EP | disclosed |
| CN-109970708-B | Cannabinoid receptor modulators | 艾尼纳制药公司 | 2022-06-21 | — | — | CN | disclosed |
| CN-114366746-A | Treatment of cancer using oxoisoindole compounds | 细胞基因公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-114344307-A | Treatment of cancer using oxoisoindole compounds | 细胞基因公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-113403338-A | Breast and ovarian cancer vaccines | 华盛顿大学商业中心 | 2021-09-17 | — | — | CN | disclosed |
| CN-108245518-B | Methods of treating cancer with 3- (4- ((4- (morpholinomethyl) benzyl) oxy) -1-oxoisoindolin-2-yl) piperidine-2, 6-dione | 细胞基因公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-106456735-B | Breast and ovarian cancer vaccines | 华盛顿大学商业中心 | 2021-06-29 | — | — | CN | disclosed |
| CN-112334135-A | Methods of treating cancer characterized by high expression levels of the spindle and centromere-associated complex subunit 3(SKA3) gene | 大学健康网络 | 2021-02-05 | — | — | CN | disclosed |
| CN-1784382-A | 7-amino-isoindolyl compounds and their pharmaceutical uses | CELGENE CORP (US) | 2006-06-07 | — | — | CN | disclosed |
| CN-1771055-A | Methods of preventing or treating T cell malignancies by administering CD2 antagonists | MEDIMMUNE INC (US) | 2006-05-10 | — | — | CN | disclosed |
| CN-1720226-A | Methods of using and compositions comprising selective cytokine inhibitory drugs for the treatment and management of myeloproliferative diseases | CELGENE CORP (US) | 2006-01-11 | — | — | CN | disclosed |
| CN-1717405-A | Benzopyranone compounds, compositions thereof, and methods of treating or preventing cancer | SIGNAL PHARM LLC (US) | 2006-01-04 | — | — | CN | disclosed |
| CN-1701071-A | Therapeutic agents useful for treating pain | EURO CELTIQUE SA (LU) | 2005-11-23 | — | — | CN | disclosed |
| CN-1697655-A | Methods and compositions for treatment and control of cancer and other diseases using immunomodulatory compounds | CELGENE CORP (US) | 2005-11-16 | — | — | CN | disclosed |
| CN-1668299-A | Methods for using JNK inhibitors for treating or preventing disease-related wasting | SIGNAL PHARM INC (US) | 2005-09-14 | — | — | CN | disclosed |
| CN-1668296-A | Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases | CELGENE CORP (US) | 2005-09-14 | — | — | CN | disclosed |
| CN-1659159-A | Benzopyranone compounds, compositions thereof, and methods of treatment therewith | SIGNAL PHARM INC (US) | 2005-08-24 | — | — | CN | disclosed |
| CN-1652772-A | (+) -2- [ 1- (3-ethoxy-4-methoxyphenyl) -2-methylsulfonylethyl ] -4-acetylaminoisoindoline-1, 3-dione, methods of use, and compositions thereof | CELGENE CORP (US) | 2005-08-10 | — | — | CN | disclosed |