Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Taurine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 3/20 | 0.93 |
| ▸ | LMNA | P02545 | 2/20 | 0.93 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.93 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.93 |
| ▸ | APP | P05067 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Taurine SCHEMBL6363956 | 0.97 | BLM (0.88) | BLMLMNASLC6A6CYP2C19APP | |
| Taurine SCHEMBL27565800 | 0.97 | BLM (0.88) | BLMLMNASLC6A6CYP2C19APP | |
| Taurine SCHEMBL30193928 | 0.97 | BLM (0.88) | BLMLMNASLC6A6CYP2C19APP | |
| Taurine SCHEMBL31366115 | 0.97 | BLM (0.88) | BLMLMNASLC6A6CYP2C19APP | |
| Taurine SCHEMBL16859744 | 0.97 | BLM (0.88) | BLMLMNASLC6A6CYP2C19APP | |
| Taurine SCHEMBL30191395 | 0.97 | — | — | |
| Taurine SCHEMBL30179154 | 0.97 | — | — | |
| Taurine SCHEMBL42632 | 0.97 | BLM (1.00) | BLMLMNASLC6A6CYP2C19APP | |
| Taurine SCHEMBL23068 | 0.97 | — | — | |
| Taurine SCHEMBL11449240 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11015152-B2 | Cleansing bars with taurine | COLGATE-PALMOLIVE COMPANY (US) | 2021-05-25 | — | — | US | claimed |
| CN-108713054-B | Cleansing bar containing taurine | 高露洁-棕榄公司 | 2020-09-29 | — | — | CN | claimed |
| EP-3383984-B1 | CLEANSING BARS WITH TAURINE | COLGATE PALMOLIVE CO (US) | 2020-03-11 | — | — | EP | claimed |
| EP-3220879-B1 | CLEANSING BARS WITH TAURINE | COLGATE PALMOLIVE CO (US) | 2020-03-04 | — | — | EP | claimed |
| CN-107001999-B | Cleansing bar containing taurine | 高露洁-棕榄公司 | 2020-02-07 | — | — | CN | claimed |
| US-10400199-B2 | Cleansing bars with taurine | COLGATE-PALMOLIVE COMPANY (US) | 2019-09-03 | — | — | US | claimed |
| US-20180355293-A1 | Cleansing Bars with Taurine | COLGATE-PALMOLIVE COMPANY (US) | 2018-12-13 | — | — | US | claimed |
| CN-108713054-A | Cleansing bars containing taurine | 高露洁-棕榄公司 | 2018-10-26 | — | — | CN | claimed |
| EP-3383984-A1 | CLEANSING BARS WITH TAURINE | Colgate-Palmolive Company (US) | 2018-10-10 | — | — | EP | claimed |
| US-20170335251-A1 | Cleansing Bars with Taurine | COLGATE-PALMOLIVE COMPANY (US) | 2017-11-23 | — | — | US | claimed |
| EP-3220879-A1 | CLEANSING BARS WITH TAURINE | Colgate-Palmolive Company (US) | 2017-09-27 | — | — | EP | claimed |
| CN-107001999-A | Cleansing bar containing taurine | 高露洁-棕榄公司 | 2017-08-01 | — | — | CN | claimed |
| WO-2017095445-A1 | CLEANSING BARS WITH TAURINE | COLGATE-PALMOLIVE COMPANY (US) | 2017-06-08 | — | — | WO | claimed |
| WO-2016089422-A1 | CLEANSING BARS WITH TAURINE | COLGATE-PALMOLIVE COMPANY (US) | 2016-06-09 | — | — | WO | claimed |
| US-20240307481-A1 | COMPOSITIONS AND METHODS FOR IMPROVING EYE FUNCTION | CROSS III WILLIAM H (US) | 2024-09-19 | — | — | US | disclosed |
| EP-3808734-B1 | THE METHOD AND PRODUCTION SYSTEM FOR FULLY RECOVERING AND TREATING TAURINE MOTHER LIQUOR | QIANGJIANG YONGAN PHARMACEUTICAL CO LTD (CN) | 2022-03-30 | — | — | EP | disclosed |
| US-20220033743-A1 | Solid Cleansing Compositions with Taurine and Methods Thereof | COLGATE-PALMOLIVE COMPANY (US) | 2022-02-03 | — | — | US | disclosed |
| EP-2239251-A1 | Process for refining 2-aminoethanesulfonic acid from crude 2-aminoethane-sulfonic acid, 2-aminoethanesulfonic acid obtained there from and use thereof | Rheln Pharma Consult GmbH (DE) | 2010-10-13 | — | — | EP | disclosed |
| CN-101857558-A | Make with extra care the method for 2-aminoethyl sulfonic acid, thus obtained 2-aminoethyl sulfonic acid and uses thereof by rough 2-aminoethyl sulfonic acid | RHELN PHARMA CONSULT GMBH | 2010-10-13 | — | — | CN | disclosed |
| CN-101466346-A | Bleed-resistant colored microparticles | CIBA HOLDING INC (CH) | 2009-06-24 | — | — | CN | disclosed |