SCHEMBL3480945

SCHEMBL3480945

COc1ccc(C(=O)c2ccccc2)c(C(=O)O)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.71
HTT P42858 2/20 0.71
MAPK1 P28482 2/20 0.71
LMNA P02545 1/20 0.71
CYP1A2 P05177 1/20 0.71
PGR P06401 1/20 0.71
CYP2D6 P10635 1/20 0.71
HPGD P15428 1/20 0.71
SLC6A2 P23975 1/20 0.71
PDE4A P27815 1/20 0.71
CYP2C19 P33261 1/20 0.71
HRH1 P35367 1/20 0.71
SLC6A3 Q01959 1/20 0.71
PDE4D Q08499 1/20 0.71
POLB P06746 4/20 0.62
MAPT P10636 2/20 0.58
NPSR1 Q6W5P4 1/20 0.58
RAB9A P51151 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
KMT2A Q03164 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL699230 0.93 ALDH1A1 (0.71) ALDH1A1HTTMAPK1LMNACYP1A2
SCHEMBL4124832 0.92 NPC1 (0.68) ALDH1A1HTTMAPK1LMNACYP1A2
SCHEMBL4833882 0.91 CDC25B (0.61) ALDH1A1HTTMAPK1LMNACYP1A2
SCHEMBL4842051 0.90 CYP2C8 (0.64) ALDH1A1HTTMAPK1LMNACYP1A2
SCHEMBL27939607 0.88 CDC25B (0.66) ALDH1A1HTTMAPK1LMNACYP1A2
SCHEMBL5307872 0.88 NPC1 (0.63) ALDH1A1HTTMAPK1LMNACYP1A2
SCHEMBL4838995 0.87 ALDH1A1 (0.66) ALDH1A1HTTMAPK1LMNACYP1A2
SCHEMBL4843372 0.87 ALDH1A1 (0.56) ALDH1A1HTTMAPK1LMNACYP1A2
SCHEMBL16311089 0.86 POLB (0.66) ALDH1A1HTTMAPK1LMNACYP1A2
SCHEMBL4843293 0.86 ALDH1A1 (0.60) ALDH1A1HTTMAPK1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114395170-A Antibacterial agent for producing modified plastics and preparation method thereof 温州市梵特日用品有限公司 2022-04-26 CN claimed
CN-103965654-A Light-fastness pigment with super-molecular intercalated structure and preparation method thereof UNIV BEIJING CHEMICAL 2014-08-06 CN claimed
CN-114395170-A Antibacterial agent for producing modified plastics and preparation method thereof 温州市梵特日用品有限公司 2022-04-26 CN disclosed
CN-114395170-A Antibacterial agent for producing modified plastics and preparation method thereof 温州市梵特日用品有限公司 2022-04-26 CN disclosed
CN-110739404-A Quantum dot light-emitting diode and preparation method thereof TCL集团股份有限公司 2020-01-31 CN disclosed
CN-103965654-B A kind of supermolecular intercalation structure of resistance to light type pigment and preparation method thereof 北京化工大学 2016-08-17 CN disclosed
CN-103965654-A Light-fastness pigment with super-molecular intercalated structure and preparation method thereof UNIV BEIJING CHEMICAL 2014-08-06 CN disclosed
CN-103619914-A Novel organopolysiloxane elastomer and use therefor DOW CORNING TORAY CO LTD 2014-03-05 CN disclosed
CN-103608384-A Novel liquid organopolysiloxane and use thereof DOW CORNING TORAY CO LTD 2014-02-26 CN disclosed
US-7781457-B2 Isoquinolinone potassium channel inhibitors MERCK SHARP & DOHME CORP. (US) 2010-08-24 US disclosed
US-7781457-B2 Isoquinolinone potassium channel inhibitors MERCK SHARP & DOHME CORP. (US) 2010-08-24 US disclosed
EP-1163372-A4 CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES PRINCETON SEPARATIONS (US) 2002-10-02 EP disclosed
EP-1163372-A1 CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES Princeton Separations (US) 2001-12-19 EP disclosed
WO-2000056933-A1 CHEMICALLY REACTIVE PLANE-RIGIDIZED CYANINE DYES AND THEIR DERIVATIVES PRINCETON SEPARATIONS (US) 2000-09-28 WO disclosed
EP-0437185-B1 Pyrroline-resp. indoline containing phthalides CIBA GEIGY AG (CH) 1995-10-18 EP disclosed
EP-0569457-B1 USE OF THIAZOLO-[2,3-A]ISOINDOLE DERIVATIVES AS ANTIVIRAL MEDICAMENTS AND NOVEL THIAZOLO- [2,3-A]ISOINDOLE DERIVATIVES BOEHRINGER MANNHEIM GMBH (DE) 1995-06-14 EP disclosed
EP-0569457-A1 USE OF THIAZOLO- 2,3-A]ISOINDOLE DERIVATIVES AS ANTIVIRAL MEDICAMENTS AND NOVEL THIAZOLO- 2,3-A]ISOINDOLE DERIVATIVES. BOEHRINGER MANNHEIM GMBH (DE) 1993-11-18 EP disclosed
US-5162544-A INDOLINE-CONTAINING PHTHALIDES CIBA-GEIGY CORPORATION (US) 1992-11-10 US disclosed
WO-1992013863-A1 USE OF THIAZOLO-[2,3-A]ISOINDOLE DERIVATIVES AS ANTIVIRAL MEDICAMENTS AND NOVEL THIAZOLO-[2,3-A]ISOINDOLE DERIVATIVES BOEHRINGER MANNHEIM GMBH (DE) 1992-08-20 WO disclosed
EP-0437185-A2 Pyrroline-resp. indoline containing phthalides CIBA-GEIGY AG (CH) 1991-07-17 EP disclosed