SCHEMBL348197

SCHEMBL348197

C1=CSc2ccccc2C=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL19744946 0.98
Water SCHEMBL19745732 0.98
SCHEMBL28340660 0.98
Acetic Acid SCHEMBL11657145 0.87 NOX1 (0.33)
SCHEMBL6199756 0.85
SCHEMBL11579149 0.81 TSHR (0.50)
SCHEMBL493616 0.78 TRPA1 (0.30)
SCHEMBL22552069 0.78 TRPA1 (0.30)
SCHEMBL6369982 0.76
Malic Acid SCHEMBL28491090 0.76 SMN1; SMN2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1786 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
WO-2024102758-A2 N-(N-AMINOALKYL)PHENANTHRIDIUNIUM SERIES OF CHLORIDE-SENSITIVE FLUOROPHORES AND METHODS OF USE THEREOF THE GENERAL HOSPITAL CORPORATION (US) 2024-05-16 WO claimed
CN-115806559-A Benzothiazepine bridged ring compound and preparation method thereof 天津理工大学 2023-03-17 CN claimed
CN-111574475-B Preparation method of halogenated benzothiepin oxide, product prepared by preparation method and application of product 西安都创医药科技有限公司 2022-09-20 CN claimed
CN-114585354-A Method for treating epileptic patients with fenfluramine 周格尼克斯国际有限公司 2022-06-03 CN claimed
EP-3972596-A1 COMBINATIONS COMPRISING BENZODIOXOL AS GLP-1R AGONISTS FOR USE IN THE TREATMENT OF NASH/NAFLD AND RELATED DISEASES Pfizer Inc. (US) 2022-03-30 EP claimed
CN-111920809-B Application of benzothiidine and salt thereof in preparation of antitumor drugs 郑州大学 2022-01-07 CN claimed
CN-113874019-A Combinations comprising benzodioxoles as GLP-1R agonists for the treatment of NASH/NAFLD and related diseases 辉瑞大药厂 2021-12-31 CN claimed
CN-113861128-A Polymerizable compound and optically anisotropic body 江苏创拓新材料有限公司 2021-12-31 CN claimed
US-20210309646-A1 DIACYLGLYCEROL ACYL TRANSFERASE 2 INHIBITORS PFIZER INC. (US) 2021-10-07 US claimed
EP-1140187-A1 COMBINATIONS FOR CARDIOVASCULAR INDICATIONS G.D. Searle LLC. (US) 2001-10-10 EP claimed
EP-1120122-A1 BONE REPAIR MATERIALS/ARTIFICIAL BONE COMPOSITIONS Takeda Chemical Industries, Ltd. (JP) 2001-08-01 EP claimed
EP-1105140-A2 BENZOTHIEPINE COMPOUNDS AS ENHANCER OF CELL DIFFERENTIATION INDUCTION FACTOR Takeda Chemical Industries, Ltd. (JP) 2001-06-13 EP claimed
WO-2000038725-A1 COMBINATIONS FOR CARDIOVASCULAR INDICATIONS G.D. SEARLE LLC (US) 2000-07-06 WO claimed
WO-2000009100-A2 BENZOTHIEPINE COMPOUNDS AS ENHANCER OF CELL DIFFERENTIATION INDUCTION FACTOR TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-02-24 WO claimed
US-5952512-A Production of optically active benzothiepin salts TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-09-14 US claimed
CN-1191538-A Production of optically active benzothiepin salts TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-08-26 CN claimed
EP-0842179-A1 PRODUCTION OF OPTICALLY ACTIVE BENZOTHIEPIN SALTS Takeda Chemical Industries, Ltd. (JP) 1998-05-20 EP claimed
WO-1997003989-A1 PRODUCTION OF OPTICALLY ACTIVE BENZOTHIEPIN SALTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-02-06 WO claimed
EP-0226320-A1 Imidazolyl thieno-benzothiepin derivatives and processes for the preparation thereof SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) 1987-06-24 EP claimed