SCHEMBL3482032

SCHEMBL3482032

O=C(c1ccccn1)c1cc(Cl)ccc1Cl

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.63
L3MBTL1 Q9Y468 2/20 0.61
NPC1 O15118 2/20 0.61
RAB9A P51151 2/20 0.61
ALDH1A1 P00352 1/20 0.61
LMNA P02545 1/20 0.61
HPGD P15428 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
TSHR P16473 1/20 0.52
AGTR1 P30556 1/20 0.52
GRM4 Q14833 3/20 0.51
HDAC6 Q9UBN7 1/20 0.51
MAPT P10636 1/20 0.51
PKM P14618 1/20 0.51
HSD17B10 Q99714 1/20 0.51
CCR9 P51686 1/20 0.51
TLR7 Q9NYK1 2/20 0.50
PRKD3 O94806 1/20 0.50
PRKCG P05129 1/20 0.50
PRKCB P05771 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28335130 0.87 KMT2A (0.63) KMT2AL3MBTL1NPC1RAB9AALDH1A1
SCHEMBL342047 0.86 RECQL (0.58) KMT2AL3MBTL1NPC1RAB9AALDH1A1
SCHEMBL31366584 0.86 RECQL (0.58) KMT2AL3MBTL1NPC1RAB9AALDH1A1
SCHEMBL14419346 0.84 CCR9 (0.52) KMT2AL3MBTL1NPC1RAB9AALDH1A1
SCHEMBL17842156 0.83 GRM4 (0.64) KMT2AL3MBTL1NPC1RAB9AALDH1A1
SCHEMBL15906618 0.82 CCR9 (0.61) KMT2AL3MBTL1NPC1RAB9AALDH1A1
SCHEMBL28335114 0.81 KMT2A (0.50) KMT2AL3MBTL1NPC1RAB9AALDH1A1
SCHEMBL5624004 0.81 RAB9A (0.73) L3MBTL1NPC1RAB9AALDH1A1LMNA
SCHEMBL9389382 0.80 MAPT (0.66) KMT2ANPC1RAB9AALDH1A1LMNA
SCHEMBL8178870 0.77 KMT2A (0.46) KMT2AL3MBTL1NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8729219-B2 Polyarylene block copolymer having sulfonic acid group and use thereof JSR CORPORATION (JP) 2014-05-20 US disclosed
US-8729219-B2 Polyarylene block copolymer having sulfonic acid group and use thereof JSR CORPORATION (JP) 2014-05-20 US disclosed
US-20130085236-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF JSR CORPORATION (JP) 2013-04-04 US disclosed
US-20130085236-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF JSR CORPORATION (JP) 2013-04-04 US disclosed
US-8273499-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2012-09-25 US disclosed
US-20120052412-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF HONDA MOTOR CO., LTD. (JP) 2012-03-01 US disclosed
US-20120052412-A1 POLYARYLENE BLOCK COPOLYMER HAVING SULFONIC ACID GROUP AND USE THEREOF HONDA MOTOR CO., LTD. (JP) 2012-03-01 US disclosed
US-20100062311-A1 MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL HONDA MOTOR CO., LTD. (JP) 2010-03-11 US disclosed
WO-1993014055-A1 PREPARATION OF 2,5-DICHLOROBENZOPHENONES MAXDEM INCORPORATED (US) 1993-07-22 WO disclosed
US-5210313-A Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids MAXDEM INCORPORATED (US) 1993-05-11 US disclosed