SCHEMBL348204

SCHEMBL348204

CCCC[Si](Cl)(CCCC)CCCC

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
LMNA P02545 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
THRB P10828 1/20 0.38
ALDH1A1 P00352 3/20 0.35
TP53 P04637 1/20 0.30
SLC22A1 O15245 2/20 0.30
SLC22A2 O15244 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704794 0.97 TSHR (0.38) TSHRLMNATDP1THRBALDH1A1
Ammonia Solution, Strong SCHEMBL27832272 0.97 TSHR (0.38) TSHRLMNATDP1THRBALDH1A1
SCHEMBL703090 0.97 TSHR (0.38) TSHRLMNATDP1THRBALDH1A1
SCHEMBL706714 0.97 TSHR (0.38) TSHRLMNATDP1THRBALDH1A1
SCHEMBL2273982 0.94 TSHR (0.35) TSHRLMNATDP1THRBALDH1A1
SCHEMBL3482229 0.94 TSHR (0.35) TSHRLMNATDP1THRBALDH1A1
SCHEMBL25338689 0.91 TSHR (0.47) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL7755459 0.91 TSHR (0.47) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL18108168 0.91 TSHR (0.47) TSHRLMNATHRBALDH1A1SLC22A1
SCHEMBL18108495 0.91 TSHR (0.47) TSHRLMNATHRBALDH1A1SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1554 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497416-B2 Acylphosphine oxide compounds and preparation methods thereof ANHUI CHICHEM CORPORATION (CN) 2025-12-16 US claimed
EP-4028379-B1 IMPROVED METHOD FOR THE PREPARATION OF CYCLOPROYL COMPOUNDS FROM ALKENES SALTIGO GMBH (DE) 2025-11-19 EP claimed
CN-120025537-A Atomic oxygen-resistant polyether-ether-ketone material for aviation, preparation method thereof and composite material 南京工业大学 2025-05-23 CN claimed
US-20250060673-A1 DEVELOPMENT STRATEGY FOR HIGH-ABSORBING METAL-CONTAINING PHOTORESISTS LAM RES CORP (US) 2025-02-20 US claimed
CN-119059879-A Cyclopropanation of substituted olefins 国际香料和香精公司 2024-12-03 CN claimed
WO-2024232632-A1 TRANSITION METAL SUPPORTED CATALYST WITH IMPROVED HYDROGENATION ACTIVITY AND USE THEREOF 한양대학교 산학협력단 2024-11-14 WO claimed
US-20240318001-A1 Thick Film Low Refractive Index Polysiloxane Claddings OPTITUNE OY (FI) 2024-09-26 US claimed
CN-118388339-A Synthesis method of plant root penetration-resistant waterproof material auxiliary agent PBE 吴顶 2024-07-26 CN claimed
CN-118289714-A Preparation method of lithium sulfide 常德市大度新材料有限公司 2024-07-05 CN claimed
EP-4370588-A1 THICK FILM LOW REFRACTIVE INDEX POLYSILOXANE CLADDINGS Optitune Oy (FI) 2024-05-22 EP claimed
JP-2001501910-A 2001-02-13 JP claimed
EP-1021388-A1 PHOSPHORYLATION PROCESS AND CATALYST PERSTORP AB (SE) 2000-07-26 EP claimed
WO-2000008069-A1 PROCESS FOR HYDROGENATING A CONJUGATED DIENE POLYMER KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2000-02-17 WO claimed
US-6005012-A DEHALOGENATION OF ORGANOMETALLIC HALIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1999-12-21 US claimed
US-5958363-A Method for making monolithic metal oxide aerogels THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1999-09-28 US claimed
US-5919552-A Coated substrates and methods XEROX CORPORATION (US) 1999-07-06 US claimed
WO-1997034853-A1 PHOSPHORYLATION PROCESS AND CATALYST PERSTORP AB (SE) 1997-09-25 WO claimed
EP-0649887-A2 Water-repellant and antiseptic coating composition DOW CORNING ASIA, Ltd. (JP) 1995-04-26 EP claimed
US-4481366-A Process for the preparation of a trifluorovinylsilane, and fluorine-containing polymer and process for its preparation SAGAMI CHEMICAL RESEARCH CENTER (JP) 1984-11-06 US claimed
EP-0119404-A1 Fluorine-containing polymer and process for its preparation SAGAMI CHEMICAL RESEARCH CENTER (JP) 1984-09-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12497416-B2 Acylphosphine oxide compounds and preparation methods thereof PHOSPHO1, PLCB1, PLCB3 TSHR 4055/4885LMNA 1456/4885TDP1 3732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.