SCHEMBL3482071

SCHEMBL3482071

Cc1cc(Cc2ccc(Cc3ccc(N)c(C)c3)cc2)ccc1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.59
ALDH1A1 P00352 8/20 0.52
CYP3A4 P08684 6/20 0.52
TSHR P16473 4/20 0.52
TDP1 Q9NUW8 3/20 0.52
GAA P10253 3/20 0.52
KDM4E B2RXH2 3/20 0.52
MAPT P10636 2/20 0.52
ESR1 P03372 2/20 0.52
ESR2 Q92731 2/20 0.52
MEN1 O00255 1/20 0.52
POLB P06746 1/20 0.52
RAB9A P51151 1/20 0.52
KMT2A Q03164 1/20 0.52
CDC25B P30305 1/20 0.45
CASP6 P55212 1/20 0.45
RCE1 Q9Y256 1/20 0.45
S100B P04271 1/20 0.45
ALOX15 P16050 2/20 0.44
HSD17B10 Q99714 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31079561 0.98 SKP2 (0.61) SKP2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL237201 0.98 SKP2 (0.61) SKP2ALDH1A1CYP3A4TSHRTDP1
Hydrochloric Acid SCHEMBL2929105 0.95 SKP2 (0.59) SKP2ALDH1A1CYP3A4TSHRTDP1
Ammonia Solution, Strong SCHEMBL22344976 0.95 SKP2 (0.59) SKP2ALDH1A1CYP3A4TSHRTDP1
Hydrochloric Acid SCHEMBL8644397 0.95 SKP2 (0.59) SKP2ALDH1A1CYP3A4TSHRTDP1
4,4'-Methylenedianiline SCHEMBL10832019 0.94 CYP3A4 (0.58) SKP2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL9309437 0.94 CYP3A4 (0.58) SKP2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL8086634 0.94 SKP2 (0.58) SKP2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL10535695 0.92 SKP2 (0.52) SKP2ALDH1A1CYP3A4TSHRTDP1
SCHEMBL27496376 0.92 SKP2 (0.56) SKP2ALDH1A1CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420764-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2013-04-16 US disclosed
US-8236917-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2012-08-07 US disclosed
US-20120178894-A1 COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER INAGAKI JYUN-ICHI (JP) 2012-07-12 US disclosed
US-20100240855-A1 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2010-09-23 US disclosed
US-7705105-B2 A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; CHISSO PETROCHEMICAL CORPORATION (JP) 2010-04-27 US disclosed
US-7507450-B2 Varnish for forming liquid crystal alignment layer and liquid crystal display element using the same CHISSO CORPORATION (JP) 2009-03-24 US disclosed
US-7373060-B2 Optical waveguide using polymer composed of silsesquioxane derivative CHISSO CORPORATION (JP) 2008-05-13 US disclosed
US-20070190344-A1 Verification of translation JNC CORPORATION (JP) 2007-08-16 US disclosed
US-20060204192-A1 Optical waveguide using polymer composed of silsesquioxane derivative JNC CORPORATION (JP) 2006-09-14 US disclosed
US-20060204680-A1 Varnish for forming liquid crystal alignment layer and liquid crystal display element using the same JNC CORPORATION (JP) 2006-09-14 US disclosed
US-6949281-B1 Varnish composition and liquid-crystal display element CHISSO CORPORATION (JP) 2005-09-27 US disclosed
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer CHISSO CORPORATION (JP) 2005-01-13 US disclosed
US-6746730-B1 VARNISH COMPOSITION WHICH COMPRISES POLYMER COMPONENT CONTAINING TWO DIFFERENT POLYAMIC ACIDS, SOLUBLE POLYIMIDE, AND SOLVENT FOR DISSOLVING POLYMER COMPONENT CHISSO CORPORATION (JP) 2004-06-08 US disclosed
US-6685997-B1 SOLUTION CONTAINING POLYAMIC ACIDS, POLYAMIDES AND POLYIMIDES; ALIGNMENT FILM; WELL BALANCED ELECTRICAL CHARACTERISTICS; ELIMINATES IMAGE STICKING CHISSO CORPORATION (JP) 2004-02-03 US disclosed
US-5001213-A Thermosetting resin compositions SHELL OIL COMPANY (US) 1991-03-19 US disclosed
US-4933423-A Thermosetting resin compositions SHELL OIL COMPANY (US) 1990-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer C1S, H1-4, H1-0 SKP2 60/4885ALDH1A1 1780/4885CYP3A4 1082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.