Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28256653 | 0.93 | ALDH1A1 (0.50) | ALDH1A1PDE10ACASP1TSHRCYP3A4 | |
| SCHEMBL28870838 | 0.93 | ALDH1A1 (0.50) | ALDH1A1PDE10ACASP1TSHRCYP3A4 | |
| SCHEMBL865950 | 0.91 | ALDH1A1 (0.56) | ALDH1A1PDE10ACASP1TSHRCYP3A4 | |
| SCHEMBL13264102 | 0.90 | SKP2 (0.47) | ALDH1A1PDE10ACASP1TSHRCYP3A4 | |
| SCHEMBL23654261 | 0.88 | ALDH1A1 (0.45) | ALDH1A1PDE10ACASP1TSHRCYP3A4 | |
| SCHEMBL27565754 | 0.88 | PDE10A (0.45) | ALDH1A1PDE10ACASP1TSHRCYP3A4 | |
| SCHEMBL25122225 | 0.88 | ALDH1A1 (0.45) | ALDH1A1PDE10ACASP1TSHRCYP3A4 | |
| SCHEMBL29126668 | 0.86 | TAAR1 (0.56) | ALDH1A1PDE10ACASP1TSHRCYP3A4 | |
| SCHEMBL22342661 | 0.86 | TYR (0.47) | ALDH1A1PDE10ACASP1TSHRCYP3A4 | |
| SCHEMBL21396180 | 0.86 | TYR (0.47) | ALDH1A1PDE10ACASP1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420764-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20120178894-A1 | COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER | INAGAKI JYUN-ICHI (JP) | 2012-07-12 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| US-7507450-B2 | Varnish for forming liquid crystal alignment layer and liquid crystal display element using the same | CHISSO CORPORATION (JP) | 2009-03-24 | — | — | US | disclosed |
| US-7373060-B2 | Optical waveguide using polymer composed of silsesquioxane derivative | CHISSO CORPORATION (JP) | 2008-05-13 | — | — | US | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20060204192-A1 | Optical waveguide using polymer composed of silsesquioxane derivative | JNC CORPORATION (JP) | 2006-09-14 | — | — | US | disclosed |
| US-20060204680-A1 | Varnish for forming liquid crystal alignment layer and liquid crystal display element using the same | JNC CORPORATION (JP) | 2006-09-14 | — | — | US | disclosed |
| US-6949281-B1 | Varnish composition and liquid-crystal display element | CHISSO CORPORATION (JP) | 2005-09-27 | — | — | US | disclosed |
| US-6946169-B1 | Polyamic acid composition, liquid crystal aligning film, and liquid crystal display element | CHISSO CORPORATION (JP) | 2005-09-20 | — | — | US | disclosed |
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | CHISSO CORPORATION (JP) | 2005-01-13 | — | — | US | disclosed |
| US-6746730-B1 | VARNISH COMPOSITION WHICH COMPRISES POLYMER COMPONENT CONTAINING TWO DIFFERENT POLYAMIC ACIDS, SOLUBLE POLYIMIDE, AND SOLVENT FOR DISSOLVING POLYMER COMPONENT | CHISSO CORPORATION (JP) | 2004-06-08 | — | — | US | disclosed |
| US-6685997-B1 | SOLUTION CONTAINING POLYAMIC ACIDS, POLYAMIDES AND POLYIMIDES; ALIGNMENT FILM; WELL BALANCED ELECTRICAL CHARACTERISTICS; ELIMINATES IMAGE STICKING | CHISSO CORPORATION (JP) | 2004-02-03 | — | — | US | disclosed |
| US-6620339-B1 | Providing polyimide resin with large pretilt angle; small residual voltage and high voltage holding ratio; reliable | CHISSO CORPORATION (JP) | 2003-09-16 | — | — | US | disclosed |
| EP-1064319-B1 | POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORP (JP) | 2003-02-19 | — | — | EP | disclosed |
| US-6316574-B1 | FOR PRODUCING ALIGNING FILMS, PROTECTION FILMS, INSULATION FILMS ELECTRICAL PROPERTIES AND RELIABILITY; FOR USE IN ELECTRONIC MATERIALS | CHISSO CORPORATION (JP) | 2001-11-13 | — | — | US | disclosed |
| EP-1042701-A1 | POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999034252-A1 | POLYAMIC ACID COMPOSITION, LIQUID CRYSTAL ALIGNING FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 1999-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | C1S, H1-4, H1-0 | ALDH1A1 1780/4885PDE10A 4251/4885CASP1 439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.