Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 4/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482511 | 0.83 | CA1 (0.47) | PTGES2CA1CA2CA9CA12 | |
| SCHEMBL7766523 | 0.80 | ALDH1A1 (0.50) | SOS1CA1CA2CA9CA12 | |
| SCHEMBL7866557 | 0.80 | NR4A1 (0.61) | ALDH1A1NR4A1RAB9AMAPTNPC1 | |
| SCHEMBL4410029 | 0.79 | ESR1 (0.48) | ALDH1A1NR4A1RAB9AMAPTNPC1 | |
| SCHEMBL3776725 | 0.79 | SOS1 (0.58) | SOS1PTGES2CA1CA2CA9 | |
| SCHEMBL9736157 | 0.77 | NR4A1 (0.42) | SOS1CA1CA2CA9CA12 | |
| SCHEMBL8509753 | 0.76 | NR4A1 (0.41) | ALDH1A1NR4A1RAB9AMAPTNPC1 | |
| SCHEMBL30287650 | 0.76 | NR4A1 (0.41) | ALDH1A1NR4A1RAB9AMAPTNPC1 | |
| SCHEMBL649033 | 0.76 | NR4A1 (0.41) | ALDH1A1NR4A1RAB9AMAPTNPC1 | |
| SCHEMBL1553198 | 0.76 | ALDH1A1 (0.46) | ALDH1A1NR4A1RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420764-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8236917-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20120178894-A1 | COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER | INAGAKI JYUN-ICHI (JP) | 2012-07-12 | — | — | US | disclosed |
| US-20100240855-A1 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| US-7507450-B2 | Varnish for forming liquid crystal alignment layer and liquid crystal display element using the same | CHISSO CORPORATION (JP) | 2009-03-24 | — | — | US | disclosed |
| US-7373060-B2 | Optical waveguide using polymer composed of silsesquioxane derivative | CHISSO CORPORATION (JP) | 2008-05-13 | — | — | US | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20060204192-A1 | Optical waveguide using polymer composed of silsesquioxane derivative | JNC CORPORATION (JP) | 2006-09-14 | — | — | US | disclosed |
| US-20060204680-A1 | Varnish for forming liquid crystal alignment layer and liquid crystal display element using the same | JNC CORPORATION (JP) | 2006-09-14 | — | — | US | disclosed |
| US-6949281-B1 | Varnish composition and liquid-crystal display element | CHISSO CORPORATION (JP) | 2005-09-27 | — | — | US | disclosed |
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | CHISSO CORPORATION (JP) | 2005-01-13 | — | — | US | disclosed |
| US-6746730-B1 | VARNISH COMPOSITION WHICH COMPRISES POLYMER COMPONENT CONTAINING TWO DIFFERENT POLYAMIC ACIDS, SOLUBLE POLYIMIDE, AND SOLVENT FOR DISSOLVING POLYMER COMPONENT | CHISSO CORPORATION (JP) | 2004-06-08 | — | — | US | disclosed |
| US-6685997-B1 | SOLUTION CONTAINING POLYAMIC ACIDS, POLYAMIDES AND POLYIMIDES; ALIGNMENT FILM; WELL BALANCED ELECTRICAL CHARACTERISTICS; ELIMINATES IMAGE STICKING | CHISSO CORPORATION (JP) | 2004-02-03 | — | — | US | disclosed |
| US-5571579-A | FORMING A POLYIMIDE FILM AND RUBBING THE SURFACE OF THE FILM | HITACHI CHEMICAL COMPANY, LTD (JP) | 1996-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | C1S, H1-4, H1-0 | SOS1 550/4885PTGES2 2396/4885CA1 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.