SCHEMBL3482759

SCHEMBL3482759

CC1(C)C(O)=CC(=O)C=C1O

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HKDC1 Q2TB90 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2988846 0.77
SCHEMBL13447522 0.70
SCHEMBL11664836 0.63
SCHEMBL5316374 0.60
SCHEMBL20269348 0.60
SCHEMBL8663021 0.58 XIAP (0.37) KDM4EMEN1USP2TP53CYP3A4
SCHEMBL13342150 0.56
SCHEMBL5457397 0.56 MAPT (0.40) KDM4EMEN1USP2TP53CYP3A4
SCHEMBL5609964 0.55
SCHEMBL2594729 0.54

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105906500-B With the filicinic acid class compound of fatty enzyme inhibition and its application 中国科学院昆明植物研究所 2018-06-26 CN claimed
CN-106397169-A Filicinic acid compounds, and pharmaceutical compositions and application thereof 中国科学院昆明植物研究所 2017-02-15 CN claimed
CN-105906500-A Filicinic acid compounds with lipase inhibition effect, and application thereof 中国科学院昆明植物研究所 2016-08-31 CN claimed
CN-105906500-B With the filicinic acid class compound of fatty enzyme inhibition and its application 中国科学院昆明植物研究所 2018-06-26 CN disclosed
CN-105906500-B With the filicinic acid class compound of fatty enzyme inhibition and its application 中国科学院昆明植物研究所 2018-06-26 CN disclosed
CN-105906500-B With the filicinic acid class compound of fatty enzyme inhibition and its application 中国科学院昆明植物研究所 2018-06-26 CN disclosed
CN-106397169-A Filicinic acid compounds, and pharmaceutical compositions and application thereof 中国科学院昆明植物研究所 2017-02-15 CN disclosed
CN-106397169-A Filicinic acid compounds, and pharmaceutical compositions and application thereof 中国科学院昆明植物研究所 2017-02-15 CN disclosed
CN-106397169-A Filicinic acid compounds, and pharmaceutical compositions and application thereof 中国科学院昆明植物研究所 2017-02-15 CN disclosed
CN-105906500-A Filicinic acid compounds with lipase inhibition effect, and application thereof 中国科学院昆明植物研究所 2016-08-31 CN disclosed
CN-105906500-A Filicinic acid compounds with lipase inhibition effect, and application thereof 中国科学院昆明植物研究所 2016-08-31 CN disclosed
CN-103349747-A Traditional Chinese medicine preparation for preventing and curing paralichthys olivaceus and sea cucumber scuticoci liatlda diseases RONGCHENG FISHERY TECHNOLOGY PROMOTION STATION 2013-10-16 CN disclosed
CN-102524309-A Botanical nematicide UNIV SHANXI 2012-07-04 CN disclosed
CN-101856406-B Chinese herbal cleaning liquid for preventing and treating cervical diseases MINGJIE LI 2012-01-04 CN disclosed
CN-102038975-A Chinese medicinal herbal plant liquid cotton gauze sanitary towel MINGJIE LI 2011-05-04 CN disclosed
US-7854946-B1 Anti-inflammatory and anti-HIV compositions and methods of use IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2010-12-21 US disclosed
CN-101856406-A Chinese herbal cleaning liquid for preventing and treating cervical diseases MINGJIE LI 2010-10-13 CN disclosed
WO-2010092162-A1 NEUROACTIVE PLANT EXTRACT FROM HYPERICUM POLYANTHEMUM UNIVERSITE DE ROUEN (FR) 2010-08-19 WO disclosed
CN-1860890-A Pesticide made from Chinese herb medicine SHENGJI GROUP CO LTD TIANJIN (CN) 2006-11-15 CN disclosed
CN-1072322-A Chinese herbal feed additive SHEN YUAN GANG (CN) 1993-05-26 CN disclosed