Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12359024 | 0.90 | NPSR1 (0.41) | NPSR1FLT3MAPTCNR2FPR1 | |
| SCHEMBL338765 | 0.84 | NPSR1 (0.41) | NPSR1FLT3MAPTCNR2FPR1 | |
| SCHEMBL12306126 | 0.78 | NPSR1 (0.47) | NPSR1FLT3MAPTCNR2FPR1 | |
| SCHEMBL342076 | 0.77 | NPSR1 (0.41) | NPSR1FLT3MAPTCNR2ALDH1A1 | |
| SCHEMBL12306124 | 0.77 | NPSR1 (0.41) | NPSR1FLT3MAPTCNR2FPR1 | |
| SCHEMBL345163 | 0.75 | NPSR1 (0.39) | NPSR1FLT3MAPTCNR2LMNA | |
| SCHEMBL12359164 | 0.75 | NPSR1 (0.39) | NPSR1FLT3MAPTCNR2FPR1 | |
| SCHEMBL338481 | 0.73 | NPSR1 (0.47) | NPSR1MAPTCNR2LMNAKMT2A | |
| SCHEMBL347028 | 0.72 | NPSR1 (0.46) | NPSR1MAPTCNR2FPR1ALDH1A1 | |
| SCHEMBL12359023 | 0.72 | NPSR1 (0.35) | NPSR1FLT3MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321319-B1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES INC (US) | 2012-03-14 | — | — | EP | disclosed |