SCHEMBL3482833

SCHEMBL3482833

Nc1ccc(CCc2ccc(CCc3ccc(N)cc3)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 1.00
MAOB P27338 5/20 0.78
MAOA P21397 3/20 0.78
ALDH1A1 P00352 2/20 0.65
CYP3A4 P08684 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
TSHR P16473 1/20 0.65
CYP19A1 P11511 5/20 0.64
LOXL2 Q9Y4K0 1/20 0.61
MEN1 O00255 1/20 0.57
MAPT P10636 1/20 0.57
KMT2A Q03164 1/20 0.57
CHKA P35790 1/20 0.54
RECQL P46063 1/20 0.54
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
TP53 P04637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL187043 1.00 GFER (1.00) GFERMAOBMAOAALDH1A1CYP3A4
SCHEMBL8164156 1.00 GFER (1.00) GFERMAOBMAOAALDH1A1CYP3A4
Hydrochloric Acid SCHEMBL8653872 0.97 GFER (0.93) GFERMAOBMAOAALDH1A1CYP3A4
SCHEMBL6362605 0.91 CYP3A4 (0.82) GFERMAOBMAOAALDH1A1CYP3A4
SCHEMBL12110688 0.91 GFER (0.82) GFERMAOBMAOAALDH1A1CYP3A4
SCHEMBL4082319 0.88 MAOB (1.00) GFERMAOBMAOAALDH1A1CYP3A4
SCHEMBL12110815 0.88 GFER (0.78) GFERMAOBMAOAALDH1A1CYP3A4
SCHEMBL12110804 0.88 GFER (0.78) GFERMAOBMAOAALDH1A1CYP3A4
SCHEMBL12110702 0.87 GFER (0.77) GFERMAOBMAOAALDH1A1CYP3A4
SCHEMBL2914010 0.87 GFER (0.77) GFERMAOBMAOAALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6949281-B1 Varnish composition and liquid-crystal display element CHISSO CORPORATION (JP) 2005-09-27 US claimed
US-6746730-B1 VARNISH COMPOSITION WHICH COMPRISES POLYMER COMPONENT CONTAINING TWO DIFFERENT POLYAMIC ACIDS, SOLUBLE POLYIMIDE, AND SOLVENT FOR DISSOLVING POLYMER COMPONENT CHISSO CORPORATION (JP) 2004-06-08 US claimed
US-11561440-B2 Photoalignment composition for the stabilization of the pre-tilt angle in liquid crystal layers Rolic Technologies AG (CH) 2023-01-24 US disclosed
EP-3125033-B1 LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2021-06-02 EP disclosed
US-10968392-B2 Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer JNC CORPORATION (JP) 2021-04-06 US disclosed
US-10782566-B2 Liquid crystal display device JNC CORPORATION (JP) 2020-09-22 US disclosed
CN-106987019-B Polyimide aerogel crosslinked by surface functionalized nanoparticles and preparation method thereof 北京航空航天大学 2020-05-08 CN disclosed
EP-3179303-B1 LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2020-04-01 EP disclosed
US-20200073181-A1 NEW PHOTOALIGNMENT COMPOSITION FOR THE STABILIZATION OF THE PRE-TILT ANGLE IN LIQUID CRYSTAL LAYERS Rolic Technologies AG (CH) 2020-03-05 US disclosed
US-10435627-B2 Liquid crystal display device JNC CORPORATION (JP) 2019-10-08 US disclosed
US-10423033-B2 Method for producing liquid crystal alignment film and liquid crystal display element using same DIC CORPORATION (JP) 2019-09-24 US disclosed
EP-1894977-A1 Inkjet ink Chisso Corporation (JP) 2008-03-05 EP disclosed
US-20080003381-A1 Overcoat film composition, color filter substrate, and liquid crystal display element CHISSO CORPORATION 2008-01-03 US disclosed
US-20070190344-A1 Verification of translation JNC CORPORATION (JP) 2007-08-16 US disclosed
US-20060204192-A1 Optical waveguide using polymer composed of silsesquioxane derivative JNC CORPORATION (JP) 2006-09-14 US disclosed
US-20060204680-A1 Varnish for forming liquid crystal alignment layer and liquid crystal display element using the same JNC CORPORATION (JP) 2006-09-14 US disclosed
US-6949281-B1 Varnish composition and liquid-crystal display element CHISSO CORPORATION (JP) 2005-09-27 US disclosed
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer CHISSO CORPORATION (JP) 2005-01-13 US disclosed
US-6746730-B1 VARNISH COMPOSITION WHICH COMPRISES POLYMER COMPONENT CONTAINING TWO DIFFERENT POLYAMIC ACIDS, SOLUBLE POLYIMIDE, AND SOLVENT FOR DISSOLVING POLYMER COMPONENT CHISSO CORPORATION (JP) 2004-06-08 US disclosed
US-6685997-B1 SOLUTION CONTAINING POLYAMIC ACIDS, POLYAMIDES AND POLYIMIDES; ALIGNMENT FILM; WELL BALANCED ELECTRICAL CHARACTERISTICS; ELIMINATES IMAGE STICKING CHISSO CORPORATION (JP) 2004-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10968392-B2 Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer DDT, DCLRE1A, DVL1 GFER 2290/4885MAOB 2266/4885MAOA 894/4885
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer C1S, H1-4, H1-0 GFER 2986/4885MAOB 3751/4885MAOA 4117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.