⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48007 | 0.82 | — | — | |
| SCHEMBL5268185 | 0.80 | — | — | |
| SCHEMBL7719771 | 0.79 | ALDH1A1 (0.44) | — | |
| SCHEMBL27714857 | 0.76 | ALDH1A1 (0.41) | — | |
| SCHEMBL6140627 | 0.75 | — | — | |
| SCHEMBL10937501 | 0.75 | ALDH1A1 (0.50) | — | |
| SCHEMBL14775232 | 0.75 | ALDH1A1 (0.42) | — | |
| Acetone SCHEMBL3081070 | 0.74 | ALDH1A1 (0.57) | — | |
| SCHEMBL4971363 | 0.73 | — | — | |
| SCHEMBL20796 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006225-B2 | Stable pharmaceutical composition | ASAHI KASEI PHARMA CORPORATION (JP) | 2015-04-14 | — | — | US | disclosed |
| EP-2236135-A1 | STABLE PHARMACEUTICAL COMPOSITION | Asahi Kasei Pharma Corporation (JP) | 2010-10-06 | — | — | EP | disclosed |
| US-20100048893-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-02-25 | — | — | US | disclosed |
| US-20100041725-A1 | STABLE PHARMACEUTICAL COMPOSITION | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-02-18 | — | — | US | disclosed |
| EP-2006271-A9 | SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2009-07-29 | — | — | EP | disclosed |
| US-20090062530-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-03-05 | — | — | US | disclosed |
| US-20090054401-A1 | Substituted bicyclic derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-02-26 | — | — | US | disclosed |
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | disclosed |
| US-7470807-B2 | Suppress production of both prostaglandins and leukotrienes and have reduced side effects; treatment of various inflammatory diseases, autoimmune diseases, allergic diseases, pain and fibrosis; for example, methyl 3-[3-acetylamino-4-cyclopentyloxy-5-(naphthalen-2-yl)phenyl]propionate | ASAHI KASEI PHARMA CORPORATION (JP) | 2008-12-30 | — | — | US | disclosed |
| EP-2006271-A2 | SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2008-12-24 | — | — | EP | disclosed |
| EP-0315518-B1 | Cephalosporins having in position 3 a substituted vinyl radical, their process for preparation, their application as medicaments, compositions containing them and intermediates | ROUSSEL UCLAF (FR) | 1994-02-16 | — | — | EP | disclosed |
| US-5243043-A | Cephalosporin antibiotics and bactericides | ROUSSEL UCLAF (FR) | 1993-09-07 | — | — | US | disclosed |
| US-5075298-A | Antibiotics | ROUSSEL UCLAF (FR) | 1991-12-24 | — | — | US | disclosed |
| US-5015473-A | Beta-lactamase inhibitors | PFIZER INC. (US) | 1991-05-14 | — | — | US | disclosed |
| US-4992431-A | Bactericides or antibiotics | ROUSSELUCLAF (FR) | 1991-02-12 | — | — | US | disclosed |
| US-4908359-A | Pharmaceuticals | Uclaf, Roussel (FR) | 1990-03-13 | — | — | US | disclosed |
| EP-0315518-A1 | Cephalosporins having in position 3 a substituted vinyl radical, their process for preparation, their application as medicaments, compositions containing them and intermediates | ROUSSEL-UCLAF (FR) | 1989-05-10 | — | — | EP | disclosed |
| EP-0008917-B1 | PENAM-3-CARBOXYLIC ACID 1,1-DIOXIDES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | PFIZER INC. (US) | 1982-11-24 | — | — | EP | disclosed |
| US-4241050-A | Penam 1,1-dioxides as beta-lactamase inhibitors | PFIZER INC. (US) | 1980-12-23 | — | — | US | disclosed |
| EP-0008917-A1 | Penam-3-carboxylic acid 1,1-dioxides, process for their preparation and pharmaceutical compositions | PFIZER INC. (US) | 1980-03-19 | — | — | EP | disclosed |