SCHEMBL348415

SCHEMBL348415

FC1(F)CC1CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22400781 1.00
SCHEMBL31522812 1.00
SCHEMBL20511468 0.71
SCHEMBL18695000 0.71
SCHEMBL1856948 0.71
SCHEMBL20609221 0.71
SCHEMBL23993499 0.69
SCHEMBL3027290 0.69
SCHEMBL21374371 0.69
SCHEMBL2486690 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087442-A1 AMINO-IMIDAZOLE ANTIBACTERIAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 WO disclosed
US-20260049080-A1 WILD TYPE KIT INHIBITORS BLUEPRINT MEDICINES CORP (US) 2026-02-19 US disclosed
EP-4650351-A1 INHIBITOR OF COMPLEMENT FACTOR B Nanjing Chia Tai Tianqing Pharmaceutical Co., Ltd. (CN) 2025-11-19 EP disclosed
US-12473289-B2 Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use AMGEN INC. (US) 2025-11-18 US disclosed
EP-4229045-B1 SUBSTITUTED ACYL SULFONAMIDES FOR TREATING CANCER BROAD INST INC (US) 2025-11-12 EP disclosed
US-12448396-B2 Methods of using heterocyclic compounds as Delta-5 Desaturase inhibitors AMGEN INC. (US) 2025-10-21 US disclosed
US-12448379-B2 Wild type kit inhibitors BLUEPRINT MEDICINES CORPORATION (US) 2025-10-21 US disclosed
US-12421211-B2 Heterocyclic compounds HOFFMANN-LA ROCHE INC. (US) 2025-09-23 US disclosed
EP-4617262-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND Kyoto University (JP) 2025-09-17 EP disclosed
US-12358879-B2 Heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-07-15 US disclosed
US-20100137299-A1 SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2010-06-03 US disclosed
WO-2010045251-A2 SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS, INC. (CA) 2010-04-22 WO disclosed
WO-2010002655-A2 COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS IRM LLC (BM) 2010-01-07 WO disclosed
WO-2009143049-A1 BICYCLIC HETEROCYCLE DERIVATIVES AND USE THEREOF AS GPR119 MODULATORS SCHERING CORPORATION (US) 2009-11-26 WO disclosed
US-20090264444-A1 Organic compounds XENON PHARMACEUTICALS INC. (CA) 2009-10-22 US disclosed
EP-0227055-B1 INSECTICIDAL PYRAZOLINES SCHERING AKTIENGESELLSCHAFT (DE) 1991-08-07 EP disclosed
US-4888340-A Insecticides pyrazolines, compositions and use SCHERING AKTIENGESELLSCHAFT (DE) 1989-12-19 US disclosed
US-4859230-A Halogencyclopropyl compounds, and use as herbicidal agents SCHERING AKTIENGESELLSCHAFT (DE) 1989-08-22 US disclosed
EP-0227055-A1 Insecticidal pyrazolines SCHERING AKTIENGESELLSCHAFT (DE) 1987-07-01 EP disclosed
US-3936462-A CNS DEPRESSANT, ANALGESIC STERLING DRUG INC. (US) 1976-02-03 US disclosed