Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030549 | 0.90 | PNMT (0.51) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL2489527 | 0.87 | PNMT (0.48) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL31757158 | 0.87 | PNMT (0.48) | PNMTHTR7HTR2BNPC1RAB9A | |
| Bromide SCHEMBL15671137 | 0.85 | PNMT (0.54) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL8436619 | 0.83 | PNMT (0.43) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL1830400 | 0.83 | PNMT (0.55) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL7037299 | 0.82 | PNMT (0.52) | PNMTHTR7HTR2BNPC1RAB9A | |
| Glycine SCHEMBL15362023 | 0.82 | PNMT (0.56) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL27861228 | 0.82 | PNMT (0.51) | PNMTHTR7HTR2BNPC1RAB9A | |
| SCHEMBL9188893 | 0.81 | PNMT (0.49) | PNMTHTR7HTR2BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009860-A1 | Device and method for analysis of interactions between biomolecules | MAX-PLANCK-GESSELLSCHAFT ZUR FODERUNG DER WISSENSCHAFTEN E.V. (DE) | 2010-01-14 | — | — | US | disclosed |
| EP-1766402-A2 | DEVICE AND METHOD FOR ANALYSIS OF INTERACTIONS BETWEEN BIOMOLECULES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin (DE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005519-A2 | DEVICE AND METHOD FOR ANALYSIS OF INTERACTIONS BETWEEN BIOMOLECULES | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2006-01-19 | — | — | WO | disclosed |
| EP-1379881-B1 | METHOD FOR DETERMINING THE SUBSTRATE SPECIFICITY OF AN ENZYMATIC ACTIVITY AND A DEVICE THEREFOR | JERINI AG (DE) | 2004-10-06 | — | — | EP | disclosed |
| EP-1379881-A2 | METHOD FOR DETERMINING THE SUBSTRATE SPECIFICITY OF AN ENZYMATIC ACTIVITY AND A DEVICE THEREFOR | Jerini AG (DE) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002083933-A2 | METHOD FOR DETERMINING THE SUBSTRATE SPECIFICITY OF AN ENZYMATIC ACTIVITY AND A DEVICE THEREFOR | JERINI AG (DE) | 2002-10-24 | — | — | WO | disclosed |