Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | UGCG | Q16739 | 2/20 | 0.42 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2072883 | 1.00 | TSHR (0.45) | TSHRL3MBTL1TDP1GBA1UGCG | |
| SCHEMBL3485268 | 1.00 | TSHR (0.45) | TSHRL3MBTL1TDP1GBA1UGCG | |
| SCHEMBL13986787 | 0.95 | L3MBTL1 (0.47) | TSHRL3MBTL1TDP1GBA1UGCG | |
| SCHEMBL11121387 | 0.90 | TSHR (0.48) | TSHRL3MBTL1TDP1TRPA1HTT | |
| SCHEMBL28425565 | 0.90 | TSHR (0.48) | TSHRL3MBTL1TDP1TRPA1HTT | |
| SCHEMBL27894678 | 0.90 | TSHR (0.48) | TSHRL3MBTL1TDP1TRPA1HTT | |
| SCHEMBL27622932 | 0.85 | TSHR (0.47) | TSHRL3MBTL1TDP1GBA1UGCG | |
| SCHEMBL27622935 | 0.85 | TSHR (0.47) | TSHRL3MBTL1TDP1GBA1UGCG | |
| SCHEMBL13573008 | 0.84 | KMT2A (0.43) | TSHRL3MBTL1TDP1MMP3MMP1 | |
| SCHEMBL10081323 | 0.83 | L3MBTL1 (0.54) | TSHRL3MBTL1TDP1GBA1UGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100003732-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 2-SUBSTITUTED PROPANAL DERIVATIVE | KANEKA CORPORATION (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-1887085-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 2-SUBSTITUTED PROPANAL DERIVATIVE | Kaneka Corporation (JP) | 2008-02-13 | — | — | EP | disclosed |