SCHEMBL3485305

SCHEMBL3485305

O=C(O)CC(N1C(=O)CCC1=O)(N1C(=O)CCC1=O)C(C(=O)O)(N1C(=O)CCC1=O)N1C(=O)CCC1=O

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
PKM P14618 1/20 0.31
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL6913374 0.98 ALDH1A1 (0.31) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL2524574 0.77
SCHEMBL3719747 0.76 ALDH1A1 (0.34) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL32675817 0.75 TSHR (0.32) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL4239001 0.75
SCHEMBL2023512 0.73
SCHEMBL2216342 0.73 ALDH1A1 (0.32) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
Ethylene Glycol SCHEMBL413417 0.72 ALDH1A1 (0.31) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
Ethylene Glycol SCHEMBL10584826 0.72 ALDH1A1 (0.31) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL6847342 0.69 MEN1 (0.31) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116744984-A Reactive dry powder hemostatic material comprising protein and a multi-functionally modified polyethylene glycol-based crosslinker 达沃有限公司 2023-09-12 CN claimed
CN-114025706-A Reactive dry powder hemostatic material comprising a nucleophile and a multifunctional modified polyethylene glycol-based cross-linker 达沃有限公司 2022-02-08 CN claimed
EP-2939697-B1 HEMOSTATIC SPONGE BAXTER INT (US) 2016-08-31 EP claimed
EP-1687041-A2 SOFT TISSUE IMPLANTS AND ANTI-SCARRING AGENTS Angiotech International AG (CH) 2006-08-09 EP claimed
WO-2005051444-A2 SOFT TISSUE IMPLANTS AND ANTI-SCARRING AGENTS ANGIOTECH INTERNATIONAL AG (CH) 2005-06-09 WO claimed
US-20240002549-A1 REACTIVE POLYSACCHARIDE-BASED HEMOSTATIC AGENT DAVOL INC. (US) 2024-01-04 US disclosed
EP-4267210-A1 REACTIVE DRY POWDERED HEMOSTATIC MATERIALS COMPRISING A PROTEIN AND A MULTIFUNCTIONALIZED MODIFIED POLYETHYLENE GLYCOL BASED CROSSLINKING AGENT Davol Inc. (US) 2023-11-01 EP disclosed
CN-116744984-A Reactive dry powder hemostatic material comprising protein and a multi-functionally modified polyethylene glycol-based crosslinker 达沃有限公司 2023-09-12 CN disclosed
US-11739166-B2 Reactive polysaccharide-based hemostatic agent DAVOL INC. (US) 2023-08-29 US disclosed
US-20220211900-A1 REACTIVE DRY POWDERED HEMOSTATIC MATERIALS COMPRISING A PROTEIN AND A MULTIFUNCTIONALIZED MODIFIED POLYETHYLENE GLYCOL BASED CROSSLINKING AGENT DAVOL INC. (US) 2022-07-07 US disclosed
WO-2022146917-A1 REACTIVE DRY POWDERED HEMOSTATIC MATERIALS COMPRISING A PROTEIN AND A MULTIFUNCTIONALIZED MODIFIED POLYETHYLENE GLYCOL BASED CROSSLINKING AGENT DAVOL INC. (US) 2022-07-07 WO disclosed
EP-3989875-A1 REACTIVE DRY POWDERED HEMOSTATIC MATERIALS COMPRISING A NUCLEOPHILE AND A MULTIFUNCTIONAL MODIFIED POLYETHYLENE GLYCOL BASED CROSSLINKING AGENT Davol Inc. (US) 2022-05-04 EP disclosed
EP-2049076-A1 METHOD FOR MAKING UP OR CARING FOR KERATINOUS SUBSTANCES WITH NONCROSSLINKED POLYROTAXANES L'Oreal (FR) 2009-04-22 EP disclosed
US-20090028957-A1 Implantable Tissue-Reactive Biomaterial Compositions and Systems, and Methods of Us Thereof DANILOFF GEORGE Y 2009-01-29 US disclosed
WO-2008015272-A1 METHOD FOR MAKING UP OR CARING FOR KERATINOUS SUBSTANCES WITH NONCROSSLINKED POLYROTAXANES L'OREAL (FR) 2008-02-07 WO disclosed
WO-2006121518-A2 ELECTRICAL DEVICES, ANTI-SCARRING AGENTS, AND THERAPEUTIC COMPOSITIONS ANGIOTECH INTERNATIONAL AG (CH) 2006-11-16 WO disclosed
WO-2006113845-A1 IMPLANTABLE TISSUE-REACTIVE BIOMATERIAL COMPOSITIONS AND SYSTEMS, AND METHODS OF USE THEREOF THERABIT, INC. (US) 2006-10-26 WO disclosed
WO-2006034467-A2 BIOCOMPATIBLE HYDROGEL COMPOSITIONS JULIAZ INC. (US) 2006-03-30 WO disclosed
WO-2005051232-A2 SOFT TISSUE IMPLANTS AND ANTI-SCARRING AGENTS ANGIOTECH INTERNATIONAL AG (CH) 2005-06-09 WO disclosed
US-20050054771-A1 Adhesive tissue repair patch ANGIOTECH AMERICA, INC. (CA) 2005-03-10 US disclosed