⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3485593 | 0.93 | — | — | |
| SCHEMBL737186 | 0.79 | — | — | |
| SCHEMBL734711 | 0.72 | — | — | |
| SCHEMBL2645518 | 0.72 | MEN1 (0.34) | — | |
| SCHEMBL29022651 | 0.65 | — | — | |
| SCHEMBL294467 | 0.65 | — | — | |
| SCHEMBL7364447 | 0.65 | — | — | |
| SCHEMBL2646326 | 0.64 | — | — | |
| SCHEMBL3459371 | 0.61 | CHRNB2 (0.31) | — | |
| SCHEMBL1101993 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791264-B2 | Benzenesulfonamide compounds and their use as blockers of calcium channels | PURDUE PHARMA L.P. (US) | 2014-07-29 | — | — | US | disclosed |
| US-8247442-B2 | Benzenesulfonamide compounds and their use | PURDUE PHARMA L.P. (US) | 2012-08-21 | — | — | US | disclosed |
| US-20100022595-A1 | Benzenesulfonamide Compounds and Their Use as Blockers of Calcium Channels | PURDUE PHARMA L.P. (CT) | 2010-01-28 | — | — | US | disclosed |
| US-20090239910-A1 | Benzenesulfonamide Compounds and Their Use | EURO-CELTIQUE S.A. (LU) | 2009-09-24 | — | — | US | disclosed |
| WO-2007118853-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS BLOCKERS OF CALCIUM CHANNELS | EURO-CELTIQUE S.A. (LU) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007110449-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE | EURO-CELTIQUE S.A. (LU) | 2007-10-04 | — | — | WO | disclosed |