Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 6/20 | 0.51 |
| ▸ | PRKACG | P22612 | 1/20 | 0.51 |
| ▸ | PRKACB | P22694 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | NTMT1 | Q9BV86 | 6/20 | 0.44 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | NAA40 | Q86UY6 | 2/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29405313 | 0.80 | PSEN1 (0.58) | — | |
| Pexiganan SCHEMBL476400 | 0.80 | PSEN1 (0.58) | — | |
| Pexiganan SCHEMBL17513878 | 0.80 | PSEN1 (0.58) | — | |
| Pexiganan SCHEMBL15247673 | 0.80 | PSEN1 (0.58) | — | |
| Pexiganan SCHEMBL487091 | 0.79 | PSEN1 (0.58) | — | |
| Acetic Acid SCHEMBL29396321 | 0.79 | PSEN1 (0.58) | — | |
| SCHEMBL29458126 | 0.73 | GLP1R (0.58) | — | |
| SCHEMBL29716608 | 0.73 | GLP1R (0.58) | — | |
| SCHEMBL29420210 | 0.73 | TFPI (0.53) | — | |
| SCHEMBL30567725 | 0.72 | BACE1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140031523-A1 | Selective Poly-N-Substituted Glycine Antibiotics | BARRON ANNELISE E (US) | 2014-01-30 | — | — | US | disclosed |
| US-8445632-B2 | Selective poly-N-substituted glycine antibiotics | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120295838-A1 | Selective poly-substituted glycine antibiotics and related compositions | BARRON ANNELISE E (US) | 2012-11-22 | — | — | US | disclosed |
| EP-2252576-A2 | SELECTIVE POLY-N-SUBSTITUTED GLYCINE ANTIBIOTICS | Northwestern University (US) | 2010-11-24 | — | — | EP | disclosed |
| US-20100036088-A1 | Selective poly-N-substituted glycine antibiotics | CHONGSIRIWATANA, NATHANIEL P. | 2010-02-11 | — | — | US | disclosed |
| WO-2009105167-A2 | SELECTIVE POLY-N-SUBSTITUTED GLYCINE ANTIBIOTICS | NORTHWESTERN UNIVERSITY (US) | 2009-08-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036088-A1 | Selective poly-N-substituted glycine antibiotics | PARG, PAM, NGLY1 | PRKACA 4730/4885PRKACG 4492/4885PRKACB 4613/4885 |
| US-20140031523-A1 | Selective Poly-N-Substituted Glycine Antibiotics | PARG, PAM, NGLY1 | PRKACA 4730/4885PRKACG 4492/4885PRKACB 4613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.