Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY10 | O00398 | 2/20 | 0.62 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.60 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.60 |
| ▸ | SELP | P16109 | 1/20 | 0.58 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30435359 | 1.00 | P2RY10 (0.62) | P2RY10LPAR1LPAR3SELPLPAR2 | |
| SCHEMBL3486656 | 1.00 | P2RY10 (0.62) | P2RY10LPAR1LPAR3SELPLPAR2 | |
| SCHEMBL31347443 | 0.93 | LPAR1 (0.68) | P2RY10LPAR1LPAR3SELPLPAR2 | |
| SCHEMBL31347412 | 0.93 | LPAR1 (0.68) | P2RY10LPAR1LPAR3SELPLPAR2 | |
| SCHEMBL31347451 | 0.93 | LPAR1 (0.68) | P2RY10LPAR1LPAR3SELPLPAR2 | |
| SCHEMBL3487492 | 0.93 | LPAR1 (0.68) | P2RY10LPAR1LPAR3SELPLPAR2 | |
| SCHEMBL31347450 | 0.93 | LPAR1 (0.68) | P2RY10LPAR1LPAR3SELPLPAR2 | |
| SCHEMBL31347445 | 0.93 | LPAR1 (0.68) | P2RY10LPAR1LPAR3SELPLPAR2 | |
| SCHEMBL31347433 | 0.93 | LPAR1 (0.68) | P2RY10LPAR1LPAR3SELPLPAR2 | |
| SCHEMBL31347418 | 0.93 | LPAR1 (0.68) | P2RY10LPAR1LPAR3SELPLPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447127-B2 | Synthetic lung surfactant and use thereof | UNIVERSITY OF ROCHESTER (US) | 2016-09-20 | — | — | US | claimed |
| EP-2812018-A2 | NOVEL SP-B&SP-C PEPTIDES, SYNTHETIC LUNG SURFACTANTS, AND USE THEREOF | University Of Rochester (US) | 2014-12-17 | — | — | EP | claimed |
| US-20140044775-A1 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2014-02-13 | — | — | US | claimed |
| US-8563683-B2 | Synthetic lung surfactant and use thereof | UNIVERSITY OF ROCHESTER (US) | 2013-10-22 | — | — | US | claimed |
| WO-2013120058-A2 | NOVEL SP-B & SP-C PEPTIDES, SYNTHETIC LUNG SURFACTANTS, AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2013-08-15 | — | — | WO | claimed |
| US-20100055164-A1 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2010-03-04 | — | — | US | claimed |
| EP-2049554-A2 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | University of Rochester Medical Center (US) | 2009-04-22 | — | — | EP | claimed |
| WO-2008011559-A2 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2008-01-24 | — | — | WO | claimed |
| US-10358465-B2 | SP-B and SP-C peptides, synthetic lung surfactants, and use thereof | Los Angeles Biomedical Research Institute at Harbor—UCLA Medical Center (US) | 2019-07-23 | — | — | US | disclosed |
| EP-3459556-A1 | SYNTHETIC ANALOGS OF LUNG SURFACTANT PROTEIN SP-C AND THEIR USE | Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (US) | 2019-03-27 | — | — | EP | disclosed |
| EP-2812018-B1 | NOVEL SP-B&SP-C PEPTIDES, SYNTHETIC LUNG SURFACTANTS, AND USE THEREOF | UNIV ROCHESTER (US) | 2018-12-05 | — | — | EP | disclosed |
| US-20180037610-A1 | NOVEL SP-B & SP-C PEPTIDES, SYNTHETIC LUNG SURFACTANTS, AND USE THEREOF | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR--UCLA MEDICAL CENTER | 2018-02-08 | — | — | US | disclosed |
| US-9815869-B2 | SP-B and SP-C peptides, synthetic lung surfactants, and use thereof | UNIVERSITY OF ROCHESTER (US) | 2017-11-14 | — | — | US | disclosed |
| US-9447127-B2 | Synthetic lung surfactant and use thereof | UNIVERSITY OF ROCHESTER (US) | 2016-09-20 | — | — | US | disclosed |
| US-20140044775-A1 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2014-02-13 | — | — | US | disclosed |
| US-8563683-B2 | Synthetic lung surfactant and use thereof | UNIVERSITY OF ROCHESTER (US) | 2013-10-22 | — | — | US | disclosed |
| WO-2013120058-A2 | NOVEL SP-B & SP-C PEPTIDES, SYNTHETIC LUNG SURFACTANTS, AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2013-08-15 | — | — | WO | disclosed |
| US-20100055164-A1 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2010-03-04 | — | — | US | disclosed |
| EP-2049554-A2 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | University of Rochester Medical Center (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008011559-A2 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | UNIVERSITY OF ROCHESTER (US) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037610-A1 | NOVEL SP-B & SP-C PEPTIDES, SYNTHETIC LUNG SURFACTANTS, AND USE THEREOF | SPG11, SGMS1, SPTSSB | P2RY10 2378/4885LPAR1 76/4885LPAR3 57/4885 |
| US-20100055164-A1 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | PHOSPHO1, SGMS1, SMPD1 | P2RY10 2120/4885LPAR1 44/4885LPAR3 27/4885 |
| US-10358465-B2 | SP-B and SP-C peptides, synthetic lung surfactants, and use thereof | SPG11, SGMS1, SPTSSB | P2RY10 2999/4885LPAR1 79/4885LPAR3 61/4885 |
| US-20140044775-A1 | SYNTHETIC LUNG SURFACTANT AND USE THEREOF | PHOSPHO1, SGMS1, SMPD1 | P2RY10 2120/4885LPAR1 44/4885LPAR3 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.