Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 7/20 | 0.42 |
| ▸ | CDK8 | P49336 | 7/20 | 0.42 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | MMP9 | P14780 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3486742 | 1.00 | CCNC (0.42) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL4831228 | 0.89 | CCNC (0.45) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL4831246 | 0.89 | CCNC (0.45) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL4834355 | 0.88 | CCNC (0.44) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL4831155 | 0.88 | CCNC (0.44) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL4831171 | 0.88 | CCNC (0.44) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL29208306 | 0.87 | CCNC (0.42) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL6434499 | 0.87 | CCNC (0.42) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL6434504 | 0.87 | CCNC (0.42) | CCNCCDK8CDK19MMP1MMP2 | |
| SCHEMBL6432602 | 0.86 | CCNC (0.39) | CCNCCDK8CDK19MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029724-A1 | SCREENING METHOD | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029724-A1 | SCREENING METHOD | NR2C2, NCOR2, NCOA2 | CCNC 3143/4885CDK8 2999/4885CDK19 2093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.