Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 7/20 | 0.39 |
| ▸ | CDK8 | P49336 | 7/20 | 0.39 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4829084 | 0.90 | BTK (0.41) | CCNCCDK8CDK19GRM5MMP1 | |
| SCHEMBL1060125 | 0.90 | BTK (0.41) | CCNCCDK8CDK19GRM5MMP1 | |
| SCHEMBL4834146 | 0.88 | CCNC (0.44) | CCNCCDK8CDK19GRM5MMP1 | |
| SCHEMBL4834135 | 0.88 | CCNC (0.44) | CCNCCDK8CDK19GRM5MMP1 | |
| SCHEMBL3486742 | 0.86 | CCNC (0.42) | CCNCCDK8CDK19NAMPTGRM5 | |
| SCHEMBL3486740 | 0.86 | CCNC (0.42) | CCNCCDK8CDK19NAMPTGRM5 | |
| SCHEMBL4825717 | 0.85 | NPC1 (0.39) | CCNCCDK8CDK19GRM5MMP1 | |
| SCHEMBL4825720 | 0.85 | NPC1 (0.39) | CCNCCDK8CDK19GRM5MMP1 | |
| SCHEMBL4831228 | 0.84 | CCNC (0.45) | CCNCCDK8CDK19NAMPTMMP1 | |
| SCHEMBL4831246 | 0.84 | CCNC (0.45) | CCNCCDK8CDK19NAMPTMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556032-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | Takeda Pharmaceutical Company Limited (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039365-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-13 | — | — | WO | disclosed |