Biotin

Biotin

SCHEMBL3486836

N[C@@H](Cc1ccc(OP(=O)(O)O)cc1)C(=O)O.O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.58
▸ MEN1 O00255 1/20 0.58
▸ ABL1 P00519 1/20 0.58
▸ LMNA P02545 1/20 0.58
▸ PKM P14618 1/20 0.58
▸ IDE P14735 1/20 0.58
▸ MAPK1 P28482 1/20 0.58
▸ KMT2A Q03164 1/20 0.58
▸ RIN1 Q13671 1/20 0.58
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ CA12 O43570 10/20 0.47
▸ CA1 P00915 10/20 0.47
▸ CA2 P00918 10/20 0.47
▸ CA9 Q16790 10/20 0.47
▸ PLG P00747 1/20 0.44
▸ PRSS1 P07477 1/20 0.44
▸ PRSS2 P07478 1/20 0.44
▸ PRSS3 P35030 1/20 0.44
▸ TPSAB1 Q15661 1/20 0.44
▸ HLCS P50747 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL392506 0.88 TDP1 (0.51) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL10618578 0.87 TDP1 (0.65) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL8366189 0.86 TDP1 (0.68) TDP1MEN1ABL1LMNAPKM
SCHEMBL10618585 0.85 TDP1 (0.65) TDP1MEN1ABL1LMNAPKM
SCHEMBL4300416 0.80 CA12 (0.68) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL8011738 0.79 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL5903513 0.79 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL8011736 0.79 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL5903509 0.79 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL20641180 0.78 TDP1 (0.85) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210041427-A1 METHODS AND COMPOSITIONS FOR PHOTOTRANSFER AMBERGEN, INC 2021-02-11 — — US disclosed
US-10088474-B2 Methods and compositions for phototransfer AMBERGEN, INC. (US) 2018-10-02 — — US disclosed
US-9910034-B2 Methods and compositions for phototransfer AMBERGEN, INC. (US) 2018-03-06 — — US disclosed
US-20180017550-A1 METHODS AND COMPOSITIONS FOR PHOTOTRANSFER AMBERGEN, INC. 2018-01-18 — — US disclosed
US-20160139113-A1 Methods and Compositions for Phototransfer AMBERGEN, INC. 2016-05-19 — — US disclosed
US-9334530-B2 Methods for making and imaging arrays that comprise a plurality of different biomolecules AMBERGEN, INC. (US) 2016-05-10 — — US disclosed
US-20160018396-A1 Methods and Compositions for Phototransfer AMBERGEN, INC. 2016-01-21 — — US disclosed
US-20150192577-A1 Methods and Compositions for Phototransfer AMBERGEN, INC. 2015-07-09 — — US disclosed
US-20150141297-A1 Methods and Compositions for Phototransfer AMBERGEN, INC. 2015-05-21 — — US disclosed
US-8932879-B2 Methods and compounds for phototransfer AMBERGEN, INC. (US) 2015-01-13 — — US disclosed
US-20100317542-A1 Methods For Detecting Biomarkers AMBERGEN, INC. 2010-12-16 — — US disclosed
US-20100311042-A1 Amplifying bisulfite-treated template AMBERGEN, INC. 2010-12-09 — — US disclosed
US-20100256015-A1 Methods For Making And Imaging Arrays AMBERGEN, INC. 2010-10-07 — — US disclosed
US-20100203651-A1 Methods and compounds for phototransfer AMBERGEN, INC. 2010-08-12 — — US disclosed
US-20100075374-A1 Methods for capturing nascent proteins AMBERGEN, INC. 2010-03-25 — — US disclosed
US-20100062451-A1 Bead-ligand-nascent protein complexes AMBERGEN, INC. 2010-03-11 — — US disclosed
US-20090286286-A1 Methods for controlling amplification AMBERGEN , INC. 2009-11-19 — — US disclosed
US-20090270278-A1 Methods and compounds for making arrays AMBERGEN, INC. 2009-10-29 — — US disclosed
US-20090264298-A1 Methods for enriching subpopulations AMBERGEN, INC. 2009-10-22 — — US disclosed
WO-2009061402-A2 METHODS AND COMPOUNDS FOR PHOTOTRANSFER AMBERGEN, INC. (US) 2009-05-14 — — WO disclosed
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