Biotin

Biotin

SCHEMBL8011736

NC(CCC(=O)O)C(=O)O.O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.77
▸ MEN1 O00255 1/20 0.77
▸ ABL1 P00519 1/20 0.77
▸ LMNA P02545 1/20 0.77
▸ PKM P14618 1/20 0.77
▸ IDE P14735 1/20 0.77
▸ MAPK1 P28482 1/20 0.77
▸ KMT2A Q03164 1/20 0.77
▸ RIN1 Q13671 1/20 0.77
▸ L3MBTL1 Q9Y468 1/20 0.77
▸ HLCS P50747 6/20 0.55
▸ FOLH1 Q04609 2/20 0.52
▸ CA12 O43570 5/20 0.49
▸ CA1 P00915 5/20 0.49
▸ CA2 P00918 5/20 0.49
▸ CA9 Q16790 5/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL8011738 1.00 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL3790437 0.92 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL693036 0.92 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL770769 0.91 TDP1 (0.71) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL5903509 0.91 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL5903513 0.91 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL1033634 0.91 TDP1 (0.69) TDP1MEN1ABL1LMNAPKM
SCHEMBL31364275 0.90 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL6813990 0.90 TDP1 (0.76) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL6813983 0.90 TDP1 (0.76) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020140388-A1 GLUTAMIC ACID GREEN CLEAN FERMENTATION PROCESS 呼伦贝尔东北阜丰生物科技有限公司 2020-07-09 — — WO disclosed
CN-107227324-A A kind of glutamic acid fermentation technique 天津科技大学 2017-10-03 — — CN disclosed
US-6083728-A PREPARING GLUTAMIC ACID; CULTURING WILD TYPE MICROORGANISM IN NUTRIENT BROTH WITH METHANOL, BIOTIN AND COPPER, RECOVERING THE EXCRETED GLUTAMIC ACID FROM THE NUTRIENT BROTH REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2000-07-04 — — US disclosed
WO-1999020785-A1 PRODUCTION OF GLUTAMATE USING WILD TYPE BACILLUS METHANOLICUS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1999-04-29 — — WO disclosed
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