Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3486848 | 0.82 | MCL1 (0.79) | MCL1SLC9A1MAPTMEN1KMT2A | |
| SCHEMBL27323248 | 0.79 | MCL1 (0.59) | MCL1SLC9A1MAPTMEN1KMT2A | |
| SCHEMBL29834903 | 0.79 | L3MBTL1 (0.67) | MCL1SLC9A1MAPTMEN1KMT2A | |
| SCHEMBL4486403 | 0.79 | L3MBTL1 (0.67) | MCL1SLC9A1MAPTMEN1KMT2A | |
| SCHEMBL8616489 | 0.78 | MCL1 (0.53) | MCL1SLC9A1MAPTMEN1KMT2A | |
| SCHEMBL28868200 | 0.77 | MCL1 (0.65) | MCL1SLC9A1MAPTMEN1KMT2A | |
| SCHEMBL27532577 | 0.76 | MCL1 (0.55) | MCL1SLC9A1MAPTMEN1KMT2A | |
| SCHEMBL17995256 | 0.75 | MCL1 (0.61) | MCL1SLC9A1MAPTMEN1KMT2A | |
| SCHEMBL1092502 | 0.75 | KDM4E (0.62) | MCL1SLC9A1MAPTMEN1KMT2A | |
| SCHEMBL16599480 | 0.74 | MCL1 (0.76) | MCL1SLC9A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118241-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2010-10-14 | — | — | WO | disclosed |