Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 12/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31678986 | 0.79 | MAPT (0.48) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6805636 | 0.79 | MAPT (0.48) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7110060 | 0.77 | POLB (0.51) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8707595 | 0.77 | MAPT (0.61) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL1368372 | 0.76 | IDO1 (0.59) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL11120012 | 0.75 | PSIP1 (0.48) | MAPTALDH1A1GAALMNANPC1 | |
| SCHEMBL13736441 | 0.75 | MAPT (0.57) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL14511403 | 0.75 | MAPT (0.44) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL28211867 | 0.74 | IDO1 (0.57) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| Acetic Acid SCHEMBL29786178 | 0.73 | KDM4E (0.49) | MAPTKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293511-B2 | Production of β-Lactam antibiotics | DSM IP ASSETS B.V. (NL) | 2012-10-23 | — | — | US | disclosed |
| US-20100009404-A1 | PRODUCTION OF BETA-LACTAM ANTIBIOTICS | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2010-01-14 | — | — | US | disclosed |
| EP-2084270-A2 | PRODUCTION OF BETA-LACTAM ANTIBIOTICS | DSMIP Assets B.V. (NL) | 2009-08-05 | — | — | EP | disclosed |
| WO-2008040731-A3 | PRODUCTION OF BETA-LACTAM ANTIBIOTICS | DSM IP ASSETS BV (NL) | 2008-05-22 | — | — | WO | disclosed |
| WO-2008040731-A2 | PRODUCTION OF BETA-LACTAM ANTIBIOTICS | DSM IP ASSETS B.V. (NL) | 2008-04-10 | — | — | WO | disclosed |