Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL691636 | 0.84 | SCN9A (0.48) | NUDT1NPC1RAB9ASCN9AMEN1 | |
| SCHEMBL18889379 | 0.72 | SCN9A (0.69) | SCN9A | |
| SCHEMBL30046504 | 0.71 | ADORA2A (0.56) | ADORA2AADORA1XDHNPC1RAB9A | |
| SCHEMBL5914189 | 0.69 | MEN1 (0.60) | ADORA1XDHNPC1RAB9ATDP1 | |
| Hydrochloric Acid SCHEMBL29100611 | 0.68 | MEN1 (0.58) | ADORA1XDHNPC1RAB9ATDP1 | |
| SCHEMBL28342834 | 0.66 | RAB9A (0.67) | XDHNPC1RAB9AMCL1MAPK1 | |
| SCHEMBL20220275 | 0.65 | MAPK1 (0.68) | ADORA2AADORA1XDHNPC1RAB9A | |
| SCHEMBL21882458 | 0.65 | MAPK1 (0.68) | ADORA2AADORA1XDHNPC1RAB9A | |
| SCHEMBL20220304 | 0.65 | MAPK1 (0.68) | ADORA2AADORA1XDHNPC1RAB9A | |
| SCHEMBL19417188 | 0.65 | ADORA2A (0.92) | ADORA2AADORA1XDHNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016296-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016296-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | ABCG2, CYP3A43, CYP3A5 | ADORA2A 227/4885ADORA1 1519/4885XDH 318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.