SCHEMBL3487364

SCHEMBL3487364

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nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.45
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5921670 1.00 MPI (0.45) MPILMNAL3MBTL1TDP1
SCHEMBL2883546 0.97 MPI (0.45) MPILMNAL3MBTL1TDP1
SCHEMBL15874622 0.97 MPI (0.45) MPILMNAL3MBTL1TDP1
SCHEMBL8588218 0.91 MPI (0.38) MPILMNA
SCHEMBL523990 0.90 MPI (0.58) MPI
SCHEMBL9117419 0.90 MPI (0.58) MPI
SCHEMBL987653 0.90 MPI (0.58) MPI
SCHEMBL10588407 0.88 MPI (0.42) MPILMNAL3MBTL1TDP1
SCHEMBL17964362 0.87 MPI (0.42) MPI
Galactose SCHEMBL18304348 0.85 MPI (0.42) MPILMNAL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220211740-A1 SIRT1-SARNA COMPOSITIONS AND METHODS OF USE BOOTSTRAP EUROPE 3.0 S.À R.L. (LU) 2022-07-07 US disclosed
US-8642010-B2 KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy DYAX CORP. (US) 2014-02-04 US disclosed
CN-102630140-A A system for transformation of the chloroplast genome of scenedesmus sp. and dunaliella sp. SAPPHIRE ENERGY INC 2012-08-08 CN disclosed
US-20100003195-A1 KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-01-07 US disclosed
EP-1311162-B1 BACILLUS THURIGIENSIS CRYSTAL PROTEIN HYBRIDS SYNGENTA PARTICIPATIONS AG (CH) 2005-06-01 EP disclosed
EP-1311162-A2 BACILLUS THURIGIENSIS CRYSTAL PROTEIN HYBRIDS Syngenta Participations AG (CH) 2003-05-21 EP disclosed
WO-2002015701-A2 BACILLUS THURINGIENSIS CRYSTAL PROTEIN HYBRIDS SYNGENTA PARTICIPATIONS AG (CH) 2002-02-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220211740-A1 SIRT1-SARNA COMPOSITIONS AND METHODS OF USE SIRT1, SARM1, SARNP MPI 3765/4885LMNA 195/4885L3MBTL1 1604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.