SCHEMBL3487367

SCHEMBL3487367

O=C(O)CN(CCN(CC(=O)O)C1CCCCC1N(CC(=O)O)CC(=O)O)CC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.54
EYA2 O00167 1/20 0.54
APP P05067 1/20 0.54
ACE P12821 1/20 0.54
BLM P54132 2/20 0.52
PMP22 Q01453 2/20 0.52
LMNA P02545 2/20 0.52
KDM4E B2RXH2 1/20 0.52
CHRM2 P08172 1/20 0.52
ADRA2A P08913 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
DRD1 P21728 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
CYP2C19 P33261 1/20 0.52
ADRA1A P35348 1/20 0.52
DRD3 P35462 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HRH3 Q9Y5N1 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2597699 1.00 TDP1 (0.54) TDP1EYA2APPACEBLM
SCHEMBL2597828 1.00 TDP1 (0.54) TDP1EYA2APPACEBLM
SCHEMBL3001043 1.00 TDP1 (0.54) TDP1EYA2APPACEBLM
SCHEMBL24732403 1.00 TDP1 (0.54) TDP1EYA2APPACEBLM
SCHEMBL2995896 1.00 TDP1 (0.54) TDP1EYA2APPACEBLM
SCHEMBL24732405 1.00 TDP1 (0.54) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL9793636 0.96 TDP1 (0.58) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL8207533 0.96 TDP1 (0.58) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL1275068 0.96 TDP1 (0.58) TDP1EYA2APPACEBLM
SCHEMBL19962167 0.94 TDP1 (0.42) TDP1EYA2APPACEBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998048844-A2 ION PARIS, METHOD FOR THE PRODUCTION AND USE THEREOF AS CONTRAST AGENTS SCHERING AKTIENGESELLSCHAFT (DE) 1998-11-05 WO claimed
WO-2025106926-A1 CONJUGATES TARGETING FIBROBLAST ACTIVATION PROTEIN AND USES THEREOF Praxis Biotech LLC (US) 2025-05-22 WO disclosed
WO-2025106939-A1 CONJUGATES TARGETING FIBROBLAST ACTIVATION PROTEIN AND USES THEREOF Praxis Biotech LLC (US) 2025-05-22 WO disclosed
EP-4448544-A2 CARBONIC ANHYDRASE IX LIGANDS 3B Pharmaceuticals GmbH (DE) 2024-10-23 EP disclosed
EP-4423110-A2 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B Pharmaceuticals GmbH (DE) 2024-09-04 EP disclosed
EP-4373529-A1 FIBROBLAST ACTIVATION PROTEIN INHIBITORS AND USE THEREOF 3B Pharmaceuticals GmbH (DE) 2024-05-29 EP disclosed
EP-4274836-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF 3B Pharmaceuticals GmbH (DE) 2023-11-15 EP disclosed
WO-2023111350-A2 CARBONIC ANHYDRASE IX LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-06-22 WO disclosed
WO-2023111350-A2 CARBONIC ANHYDRASE IX LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-06-22 WO disclosed
WO-2023072971-A2 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-05-04 WO disclosed
US-20100068151-A1 MULTIMODALITY MOLECULAR IMAGING WITH THERAPEUTIC CONJUGATES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-03-18 US disclosed
EP-1846042-A2 CONJUGATES FOR DUAL IMAGING AND RADIOCHEMOTHERAPY: COMPOSITION, MANUFACTURING, AND APPLICATIONS Board of Regents, The University of Texas System (US) 2007-10-24 EP disclosed
US-20070196275-A1 Diagnostic Imaging Compositions, Their Methods Of Synthesis And Use NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-08-23 US disclosed
US-7214545-B2 Element-coded affinity tags THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-05-08 US disclosed
US-20070071673-A1 Trifunctional reagent for conjugation to a biomolecule MITRA MEDICAL TECHNOLOGY AB (SE) 2007-03-29 US disclosed
US-20070071673-A1 Trifunctional reagent for conjugation to a biomolecule MITRA MEDICAL TECHNOLOGY AB (SE) 2007-03-29 US disclosed
WO-2006074272-A2 CONJUGATES FOR DUAL IMAGING AND RADIOCHEMOTHERAPY: COMPOSITION, MANUFACTURING, AND APPLICATIONS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2006-07-13 WO disclosed
EP-1389090-A2 DIAGNOSTIC IMAGING COMPOSITIONS, THEIR METHODS OF SYNTHESIS AND USE Board of Regents, The University of Texas System (US) 2004-02-18 EP disclosed
US-20030003048-A1 Diagnostic imaging compositions, their methods of synthesis and use NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-01-02 US disclosed
WO-2002087498-A2 DIAGNOSTIC IMAGING COMPOSITIONS, THEIR METHODS OF SYNTHESIS AND USE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2002-11-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070071673-A1 Trifunctional reagent for conjugation to a biomolecule UACA, TNFSF11, CD40 TDP1 3549/4885EYA2 1832/4885APP 3423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.