⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1307873 | 0.78 | — | — | |
| SCHEMBL13518555 | 0.76 | — | — | |
| SCHEMBL348396 | 0.74 | NAAA (0.38) | — | |
| SCHEMBL7661380 | 0.72 | — | — | |
| SCHEMBL78004 | 0.72 | — | — | |
| SCHEMBL5752779 | 0.72 | — | — | |
| SCHEMBL9414580 | 0.71 | MKNK1 (0.33) | — | |
| SCHEMBL348980 | 0.70 | — | — | |
| SCHEMBL8193183 | 0.70 | NAAA (0.44) | — | |
| SCHEMBL25097417 | 0.69 | NAAA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273599-B1 | PROCESS FOR PREPARING 2BETA-SUBSTITUTED-METHYL-PENICILLIN DERIVATIVES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1992-04-01 | — | — | EP | claimed |
| US-4933444-A | Process for preparing 2β-substituted-methylpenicillin derivatives | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1990-06-12 | — | — | US | claimed |
| US-4895941-A | Process for preparing 2α-methyl-2β-(1,2,3-triazol-1-yl)methylpenam-3α-carboxylic acid derivatives | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1990-01-23 | — | — | US | claimed |
| EP-0273599-A1 | Process for preparing 2beta-substituted-methyl-penicillin derivatives | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-07-06 | — | — | EP | claimed |
| US-4092474-A | Cephalosporins having a metaloxy group in 3-substituent | SHIONOGI & CO., LTD. (JA) | 1978-05-30 | — | — | US | claimed |
| EP-2275433-B1 | METASTIN DERIVATIVE AND USE THEREOF | UNIV KYOTO (JP) | 2017-06-07 | — | — | EP | disclosed |
| US-8778871-B2 | Metastin derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-07-15 | — | — | US | disclosed |
| US-8765909-B2 | Metastin derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-07-01 | — | — | US | disclosed |
| US-8592379-B2 | Metastin derivative and use thereof | KYOTO UNIVERSITY (JP) | 2013-11-26 | — | — | US | disclosed |
| US-8361968-B2 | Metastin derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-01-29 | — | — | US | disclosed |
| US-20120015868-A1 | Metastin derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-01-19 | — | — | US | disclosed |
| US-20110312898-A1 | PROPHYLACTIC / THERAPEUTIC AGENT FOR CANCER | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-12-22 | — | — | US | disclosed |
| US-4405617-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-09-20 | — | — | US | disclosed |
| US-4399278-A | 7-AMINO-2 OR 3-CEPHEM-4-CARBOXY COMPOUNDS HAVING ANTIBACTERIAL PROPERTIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-08-16 | — | — | US | disclosed |
| EP-0010313-B1 | 3,7-DISUBSTITUTED-2- OR -3-CEPHEM-4-CARBOXYLIC ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-01-26 | — | — | EP | disclosed |
| US-4327093-A | TREATING INFECTIONS DISEASES, ANTIBACTERIAL ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-04-27 | — | — | US | disclosed |
| EP-0033965-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-19 | — | — | EP | disclosed |
| EP-0029998-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-06-10 | — | — | EP | disclosed |
| EP-0010313-A1 | 3,7-Disubstituted-2- or -3-cephem-4-carboxylic acid compounds, pharmaceutical compositions containing them and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-04-30 | — | — | EP | disclosed |
| US-4092474-A | Cephalosporins having a metaloxy group in 3-substituent | SHIONOGI & CO., LTD. (JA) | 1978-05-30 | — | — | US | disclosed |