Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 5/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | CCR1 | P32246 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3483760 | 1.00 | TP53 (0.53) | TP53MEN1LMNAKMT2ACTSK | |
| SCHEMBL1644719 | 1.00 | TP53 (0.53) | TP53MEN1LMNAKMT2ACTSK | |
| SCHEMBL5898129 | 0.86 | CTSK (0.59) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL5898328 | 0.86 | ATM (0.60) | TP53MEN1LMNAKMT2ACTSK | |
| SCHEMBL5325045 | 0.86 | CTSK (0.59) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL5325046 | 0.86 | CTSK (0.59) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL4870019 | 0.85 | CTSK (0.50) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL27752931 | 0.84 | POLB (0.57) | MEN1LMNAKMT2ACTSKCTSL | |
| SCHEMBL16695336 | 0.83 | PPARA (0.56) | TP53MEN1KMT2ACTSKCTSL | |
| SCHEMBL1644083 | 0.83 | TP53 (0.55) | TP53MEN1LMNAKMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247337-A | Method for asymmetrically synthesizing 1, 2-trans-amino alcohol and derivative thereof | 凯特立斯（深圳）科技有限公司 | 2023-12-19 | — | — | CN | disclosed |
| EP-2257536-A2 | CYCLIC DIARYL ETHER AS ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | Amira Pharmaceuticals, Inc. (US) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009102893-A2 | CYCLIC DIARYL ETHER COMPOUNDS AS ANTAGONISTS OF PROSTAGLANDIN D2 receptors | AMIRA PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |