Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.63 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.52 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3487625 | 0.96 | FAAH (0.60) | FAAHS1PR4S1PR1S1PR3MEN1 | |
| SCHEMBL3487844 | 0.92 | S1PR1 (0.55) | FAAHS1PR4S1PR1S1PR3MEN1 | |
| SCHEMBL3488416 | 0.90 | FAAH (0.79) | FAAHMEN1USP2ALDH1A1LMNA | |
| SCHEMBL3487569 | 0.90 | FAAH (0.79) | FAAHMEN1USP2ALDH1A1LMNA | |
| SCHEMBL3490532 | 0.86 | FAAH (0.76) | FAAHMEN1USP2ALDH1A1LMNA | |
| SCHEMBL11837534 | 0.84 | S1PR4 (0.60) | S1PR4S1PR1S1PR3MEN1USP2 | |
| SCHEMBL4685776 | 0.83 | S1PR4 (0.57) | S1PR4S1PR1S1PR3MEN1USP2 | |
| SCHEMBL3487635 | 0.82 | FAAH (0.65) | FAAHS1PR4S1PR1S1PR3LMNA | |
| SCHEMBL3488458 | 0.82 | FAAH (0.65) | FAAHS1PR4S1PR1S1PR3LMNA | |
| SCHEMBL9663932 | 0.81 | S1PR1 (0.67) | S1PR4S1PR1S1PR3MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048727-A1 | PERFLUOROKETONE COMPOUNDS AND USES THEREOF | DAVID SAMUEL | 2010-02-25 | — | — | US | disclosed |
| US-20100048727-A1 | PERFLUOROKETONE COMPOUNDS AND USES THEREOF | DAVID SAMUEL | 2010-02-25 | — | — | US | disclosed |
| EP-2139836-A1 | PERFLUOROKETONE COMPOUNDS AND USES THEREOF | The Royal Institution for the Advancement of Learning/McGill University (CA) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008122119-A1 | PERFLUOROKETONE COMPOUNDS AND USES THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048727-A1 | PERFLUOROKETONE COMPOUNDS AND USES THEREOF | PLA2G1B, PLA2G4B, PLA2G2E | FAAH 26/4885S1PR4 311/4885S1PR1 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.