Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | FABP7 | O15540 | 2/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3487402 | 0.81 | EPHX2 (0.45) | EPHX2KMT2ACTSKMDM4TP53 | |
| SCHEMBL1967548 | 0.74 | EPHX2 (0.46) | EPHX2KMT2ACTSKMDM4TP53 | |
| SCHEMBL1967550 | 0.73 | GDA (0.52) | EPHX2KMT2A | |
| SCHEMBL14062476 | 0.71 | KMT2A (0.43) | EPHX2KMT2A | |
| SCHEMBL14338159 | 0.70 | EPHX2 (0.50) | EPHX2KMT2ACTSKMDM4TP53 | |
| SCHEMBL3485982 | 0.68 | EPHX2 (0.43) | EPHX2KMT2ACTSKMDM4TP53 | |
| SCHEMBL8366872 | 0.66 | EPHX2 (0.75) | EPHX2KMT2AFABP7FABP5CASP3 | |
| SCHEMBL30563238 | 0.66 | KMT2A (0.44) | EPHX2KMT2AFABP7FABP5CASP3 | |
| SCHEMBL4254975 | 0.66 | EPHX2 (0.53) | EPHX2KMT2AFABP7FABP5CASP3 | |
| SCHEMBL5188515 | 0.66 | EPHX2 (0.53) | EPHX2KMT2AMDM4TP53FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097433-A2 | OLIGONUCLEOTIDE ARRAYS | Katholieke Universiteit Leuven (BE) | 2009-09-09 | — | — | EP | claimed |
| WO-2008037036-A2 | OLIGONUCLEOTIDE ARRAYS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-04-03 | — | — | WO | claimed |
| US-20100009865-A1 | OLIGONUCLEOTIDE ARRAYS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2010-01-14 | — | — | US | disclosed |
| EP-2097433-A2 | OLIGONUCLEOTIDE ARRAYS | Katholieke Universiteit Leuven (BE) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008037036-A2 | OLIGONUCLEOTIDE ARRAYS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-04-03 | — | — | WO | disclosed |