Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967548 | 0.84 | EPHX2 (0.46) | EPHX2KMT2A | |
| SCHEMBL1937112 | 0.78 | PNP (0.40) | GDAXDH | |
| SCHEMBL1969325 | 0.78 | BRD4 (0.53) | EPHX2KMT2A | |
| SCHEMBL3487402 | 0.76 | EPHX2 (0.45) | EPHX2KMT2A | |
| SCHEMBL14062476 | 0.75 | KMT2A (0.43) | EPHX2KMT2A | |
| SCHEMBL31093422 | 0.75 | GDA (0.74) | GDAXDH | |
| SCHEMBL3488066 | 0.73 | EPHX2 (0.43) | EPHX2KMT2A | |
| SCHEMBL4254975 | 0.72 | EPHX2 (0.53) | EPHX2KMT2A | |
| SCHEMBL14338159 | 0.72 | EPHX2 (0.50) | EPHX2KMT2A | |
| SCHEMBL1970070 | 0.72 | GDA (0.58) | GDA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10287313-B2 | RNA monomers containing 0-acetal levulinyl ester groups and their use in RNA microarrays | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2019-05-14 | — | — | US | claimed |
| US-20160340382-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2016-11-24 | — | — | US | claimed |
| CN-102639552-B | RNA monomer containing O-acetal levulinyl ester group (O-acetal levulinyl ester) and application thereof in RNA microarray | THE ROYAL INSTITUTE FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2016-05-25 | — | — | CN | claimed |
| EP-2334692-B1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | UNIV MCGILL (CA) | 2016-04-13 | — | — | EP | claimed |
| US-9249175-B2 | RNA monomers containing O-acetal levulinyl ester groups and their use in RNA microarrays | THE ROYAL INSTITUTE FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2016-02-02 | — | — | US | claimed |
| CN-102639552-A | RNA monomer containing O-acetal levulinyl ester group and application thereof in RNA microarray | UNIV MCGILL | 2012-08-15 | — | — | CN | claimed |
| US-20120178638-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-12 | — | — | US | claimed |
| EP-2334692-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | The Royal Institution for the Advancement of Learning / McGill University (CA) | 2011-06-22 | — | — | EP | claimed |
| WO-2010025566-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2010-03-11 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10287313-B2 | RNA monomers containing 0-acetal levulinyl ester groups and their use in RNA microarrays | EFTUD2, RNMT, NSUN2 | GDA 539/4885EPHX2 2432/4885KMT2A 1798/4885 |
| US-20160340382-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | EFTUD2, RNMT, RNGTT | GDA 562/4885EPHX2 2195/4885KMT2A 1746/4885 |
| US-20120178638-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | EFTUD2, RNMT, RNGTT | GDA 562/4885EPHX2 2195/4885KMT2A 1746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.