Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.73 |
| ▸ | HPGD | P15428 | 4/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | CASP1 | P29466 | 2/20 | 0.73 |
| ▸ | CASP7 | P55210 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 5/20 | 0.71 |
| ▸ | GLA | P06280 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.60 |
| ▸ | CRHBP | P24387 | 2/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21641647 | 0.92 | ALDH1A1 (0.86) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EHPGD | |
| SCHEMBL3486042 | 0.87 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EHPGD | |
| SCHEMBL3486858 | 0.86 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EHPGD | |
| SCHEMBL31218561 | 0.82 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EHPGD | |
| SCHEMBL3486899 | 0.81 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EHPGD | |
| SCHEMBL11704650 | 0.79 | MAPT (1.00) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EMAPK1 | |
| SCHEMBL11708510 | 0.79 | GAA (0.72) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EHPGD | |
| SCHEMBL11436371 | 0.78 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EHPGD | |
| SCHEMBL3486902 | 0.78 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EMAPK1 | |
| SCHEMBL3487128 | 0.77 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2L3MBTL1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2100507-B1 | QUINAZOLINE DERIVATIVES CAPABLE OF INHIBITING CYTOKININ SIGNALING | SUMITOMO CHEMICAL CO (JP) | 2015-02-25 | — | — | EP | disclosed |
| US-8722580-B2 | Agent for inhibiting cytokinin signaling | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20100056377-A1 | AGENT FOR INHIBITING CYTOKININ SIGNALING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |
| CN-101588716-A | Substance capable of inhibiting cytokinin signaling | SUMITOMO CHEMICAL CO (JP) | 2009-11-25 | — | — | CN | disclosed |
| EP-2100507-A1 | SUBSTANCE CAPABLE OF INHIBITING CYTOKININ SIGNALING | Sumitomo Chemical Company, Limited (JP) | 2009-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056377-A1 | AGENT FOR INHIBITING CYTOKININ SIGNALING | CROCC, STAT3, GRK6 | ALDH1A1 2316/4885SMN1; SMN2 4884/4885L3MBTL1 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.