⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27601581 | 0.79 | — | — | |
| SCHEMBL8833247 | 0.73 | — | — | |
| SCHEMBL28103656 | 0.70 | — | — | |
| SCHEMBL1651477 | 0.70 | — | — | |
| SCHEMBL27945172 | 0.70 | — | — | |
| SCHEMBL5456313 | 0.70 | — | — | |
| SCHEMBL1741742 | 0.70 | — | — | |
| SCHEMBL978922 | 0.70 | — | — | |
| SCHEMBL596389 | 0.70 | — | — | |
| SCHEMBL9635659 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | CENGENT THERAPEUTICS (US) | 2007-08-23 | — | — | US | claimed |
| WO-2005027856-A2 | INHIBITORS OF ANTHRAX LETHAL FACTOR | CENGENT THERAPEUTICS (US) | 2005-03-31 | — | — | WO | claimed |
| CN-115754052-A | Non-target metabonomics method for citrus gonggan under low-temperature storage and application | 仲恺农业工程学院 | 2023-03-07 | — | — | CN | disclosed |
| US-11364304-B2 | Crosslinked micellar spherical nucleic acids | NORTHWESTERN UNIVERSITY (US) | 2022-06-21 | — | — | US | disclosed |
| CN-106701847-B | Method for preparing euphorbia lathyris diterpene alkane type compound by conversion | 复旦大学 | 2021-09-07 | — | — | CN | disclosed |
| US-20190275166-A1 | MICELLAR SPHERICAL NUCLEIC ACIDS FROM THERMORESPONSIVE, TRACELESS TEMPLATES | NORTHWESTERN UNIVERSITY | 2019-09-12 | — | — | US | disclosed |
| US-10377745-B2 | Heterocyclic compounds as NaV channel inhibitors and uses thereof | MERCK PATENT GMBH (DE) | 2019-08-13 | — | — | US | disclosed |
| WO-2018039629-A2 | MICELLAR SPHERICAL NUCLEIC ACIDS FROM THERMORESPONSIVE, TRACELESS TEMPLATES | NORTHWESTERN UNIVERSITY (US) | 2018-03-01 | — | — | WO | disclosed |
| US-20170233377-A1 | HETEROCYCLIC COMPOUNDS AS NAV CHANNEL INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-08-17 | — | — | US | disclosed |
| US-8268994-B2 | Fused ring heterocycle kinase modulators | SGX PHARMACEUTICALS, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20100036118-A1 | Fused Ring Heterocycle Kinase Modulators | SGX PHARMACEUTICALS, INC. | 2010-02-11 | — | — | US | disclosed |
| WO-1993006085-A1 | PYRIDINE COMPOUNDS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-01 | — | — | WO | disclosed |
| EP-0593464-A4 | BENZOIC ACID DERIVATIVES. | SMITHKLINE BEECHAM CORP (US) | 1993-02-12 | — | — | EP | disclosed |
| WO-1991018601-A1 | BENZOIC ACID DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |
| US-5034531-A | Viricides | SCHERING CORPORATION (US) | 1991-07-23 | — | — | US | disclosed |
| US-4968803-A | FLUORINE AS OXIDANT | ALLIED-SIGNAL INC. (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0134828-B1 | METHOD FOR THE PREPARATION OF 2-HYDROXYPYRIDINES STARTING FROM 2-PYRIDINCARBOXYLIC ACID-N-OXIDES | LONZA AG (CH) | 1989-04-05 | — | — | EP | disclosed |
| US-4609734-A | Process for the production of 2-hydroxypyridines from 2-pyridine carboxylic acid-N-oxides | LONZA LTD. (CH) | 1986-09-02 | — | — | US | disclosed |
| US-4556716-A | HALOGENATION OF THE 2-CARBOXYLPYRIDINE OXIDE | LONZA LTD. (CH) | 1985-12-03 | — | — | US | disclosed |
| EP-0134828-A1 | Method for the preparation of 2-hydroxypyridines starting from 2-pyridincarboxylic acid-N-oxides | LONZA AG (CH) | 1985-03-27 | — | — | EP | disclosed |