SCHEMBL5456313

SCHEMBL5456313

NC1(C(=O)O)C=CC=CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6582970 0.82
SCHEMBL9368815 0.77
SCHEMBL2499734 0.75
SCHEMBL28328358 0.72
SCHEMBL8833247 0.71
SCHEMBL6726425 0.71
SCHEMBL2537166 0.70 HSD11B1 (0.35)
SCHEMBL3488485 0.70
SCHEMBL29092388 0.70
SCHEMBL978922 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110156975-A The preparation method and applications of amine-terminated hyperbrancedization aliphatic polyester 威海晨源分子新材料有限公司 2019-08-23 CN claimed
US-4909911-A Process for catalytically reducing dioxygen using dirhodium complexes UNIVERSITY OF HOUSTON (US) 1990-03-20 US claimed
US-20240307427-A1 REMDESIVIR COCRYSTAL, COMPOSITIONS AND METHODS THEREOF VERSITECH LIMITED (CN) 2024-09-19 US disclosed
CN-118638154-A Ruidexiwei eutectic, composition and method thereof 港大科桥有限公司 2024-09-13 CN disclosed
CN-113851656-B Negative electrode piece and lithium ion battery comprising same 珠海冠宇电池股份有限公司 2023-08-15 CN disclosed
CN-110156975-A The preparation method and applications of amine-terminated hyperbrancedization aliphatic polyester 威海晨源分子新材料有限公司 2019-08-23 CN disclosed
US-20180186801-A1 SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS GLAXOSMITHKLINE LLC 2018-07-05 US disclosed
US-9957271-B2 Substituted bicyclic aza-heterocycles and analogues as sirtuin modulators GLAXOSMITHKLINE LLC (US) 2018-05-01 US disclosed
EP-2768509-B1 SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS GLAXOSMITHKLINE LLC (US) 2017-03-22 EP disclosed
US-20140349993-A1 SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS GLAXOSMITHKLINE LLC 2014-11-27 US disclosed
WO-2013059587-A9 SUBSTITUTED BICYCLIC AZA-HETEROCYCLES AND ANALOGUES AS SIRTUIN MODULATORS GLAXOSMITHKLINE LLC (US) 2014-10-23 WO disclosed
US-4128553-A HERBICIDE THE DOW CHEMICAL COMPANY (US) 1978-12-05 US disclosed
US-4128551-A HERBICIDE THE DOW CHEMICAL CO. (US) 1978-12-05 US disclosed
US-4098792-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-07-04 US disclosed
US-4085279-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-18 US disclosed
US-4085278-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-18 US disclosed
US-4082758-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-04 US disclosed
US-4082759-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-04 US disclosed
US-4058533-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1977-11-15 US disclosed
US-4014888-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1977-03-29 US disclosed