⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL616019 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL28869240 | 0.61 | — | — | |
| SCHEMBL931784 | 0.61 | — | — | |
| SCHEMBL993107 | 0.59 | — | — | |
| SCHEMBL28448992 | 0.55 | — | — | |
| SCHEMBL2489445 | 0.54 | — | — | |
| Hydrochloric Acid SCHEMBL2262288 | 0.53 | — | — | |
| Hydrochloric Acid SCHEMBL2261252 | 0.53 | — | — | |
| SCHEMBL19266356 | 0.50 | — | — | |
| SCHEMBL2489548 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030109559-A1 | N-(3-amino-2-hydroxy-propyl)substituted alkylamide compounds | PHARMACIA & UPJOHN COMPANY | 2003-06-12 | — | — | US | claimed |
| EP-0328830-A1 | 4-Heteropentacyclic-4- N-(phenyl)amido piperidine compounds | Ohmeda Pharmaceutical Products Division Inc. (US) | 1989-08-23 | — | — | EP | claimed |
| US-4831192-A | Methods of preparing 4-heteropentacyclic-4-(N-phenyl)amido) piperidine derivatives and intermediate compounds | BOC, INC. (US) | 1989-05-16 | — | — | US | claimed |
| US-4791120-A | ANALGESICS | THE BOC GROUP, INC. (US) | 1988-12-13 | — | — | US | claimed |
| US-20100048590-A1 | N-(3-AMINO-2-HYDROXY-PROPYL) SUBSTITUTED ALKYLAMIDE COMPOUNDS | GAILUNAS ANDREA | 2010-02-25 | — | — | US | disclosed |
| US-7589094-B2 | N- (3-amino-2-hydroxy-propyl) substituted alkylamide compounds | ELAN PHARMACEUTICALS, INC. (US) | 2009-09-15 | — | — | US | disclosed |
| US-20060194817-A1 | N- (3-amino-2-hydroxy-propyl) substituted alkylamide compounds | ELAN PHARMACEUTICALS, INC. | 2006-08-31 | — | — | US | disclosed |
| US-20030109559-A1 | N-(3-amino-2-hydroxy-propyl)substituted alkylamide compounds | PHARMACIA & UPJOHN COMPANY | 2003-06-12 | — | — | US | disclosed |
| US-4871749-A | ANALGESICS, ANESTHETICS; SIDE EFFECT REDUCTION | BOC, INC. (US) | 1989-10-03 | — | — | US | disclosed |
| EP-0328830-A1 | 4-Heteropentacyclic-4- N-(phenyl)amido piperidine compounds | Ohmeda Pharmaceutical Products Division Inc. (US) | 1989-08-23 | — | — | EP | disclosed |
| EP-0328830-A1 | 4-Heteropentacyclic-4- N-(phenyl)amido piperidine compounds | Ohmeda Pharmaceutical Products Division Inc. (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4831192-A | Methods of preparing 4-heteropentacyclic-4-(N-phenyl)amido) piperidine derivatives and intermediate compounds | BOC, INC. (US) | 1989-05-16 | — | — | US | disclosed |
| US-4791120-A | ANALGESICS | THE BOC GROUP, INC. (US) | 1988-12-13 | — | — | US | disclosed |