⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3489039 | 0.61 | — | — | |
| SCHEMBL930455 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL28869240 | 0.52 | — | — | |
| SCHEMBL2489548 | 0.50 | — | — | |
| SCHEMBL625895 | 0.50 | — | — | |
| SCHEMBL11615305 | 0.47 | — | — | |
| SCHEMBL654923 | 0.46 | — | — | |
| SCHEMBL7423030 | 0.45 | — | — | |
| SCHEMBL3477835 | 0.43 | — | — | |
| SCHEMBL722089 | 0.39 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150364-A1 | PYRAZOLOPYRIMIDINE JAK INHIBITOR COMPOUNDS AND METHODS | GENENTECH, INC. (US) | 2024-05-09 | — | — | US | disclosed |
| WO-2023086539-A2 | BCAT2 INHIBITORS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| US-20220389020-A1 | PYRAZOLOPYRIMIDINE JAK INHIBITOR COMPOUNDS AND METHODS | GENENTECH, INC. (US) | 2022-12-08 | — | — | US | disclosed |
| EP-3670514-A1 | PYRAZOLOPYRIMIDINE JAK INHIBITOR COMPOUNDS AND METHODS | Genentech, Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| EP-3333169-A1 | PYRAZOLOPYRIMIDINE JAK INHIBITOR COMPOUNDS AND METHODS | Genentech, Inc. (US) | 2018-06-13 | — | — | EP | disclosed |
| US-20170283424-A1 | PYRAZOLOPYRIMIDINE JAK INHIBITOR COMPOUNDS AND METHODS | GENENTECH, INC. (US) | 2017-10-05 | — | — | US | disclosed |
| US-9562033-B2 | Inhibitors of viral replication, their process of preparation and their therapeutical uses | LABORATOIRE BIODIM (FR) | 2017-02-07 | — | — | US | disclosed |
| US-20160039783-A1 | Inhibitors of Viral Replication, Their Process of Preparation and Their Therapeutical Uses | HIVIH (FR) | 2016-02-11 | — | — | US | disclosed |
| US-9221841-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2015-12-29 | — | — | US | disclosed |
| EP-2903983-A1 | INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES | LABORATOIRE BIODIM (FR) | 2015-08-12 | — | — | EP | disclosed |
| EP-2193119-A1 | 4-(4-PYRIDINYL)-BENZAMIDES AND THEIR USE AS ROCK ACTIVITY MODULATORS | Abbott GmbH & Co. KG (DE) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009027392-A1 | 4-(4-PYRIDINYL)-BENZAMIDES AND THEIR USE AS ROCK ACTIVITY MODULATORS | ABBOTT GMBH & CO. KG (DE) | 2009-03-05 | — | — | WO | disclosed |
| EP-1879886-A1 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | Array Biopharma, Inc. (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006119146-A1 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2006-11-09 | — | — | WO | disclosed |
| US-20060247178-A1 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA, INC. | 2006-11-02 | — | — | US | disclosed |
| EP-1273006-B1 | USE OF LIGHT-ABSORBING COMPOUNDS IN THE INFORMATION LAYER OF OPTICAL DATA CARRIERS, AND OPTICAL DATA CARRIERS | BAYER CHEMICALS AG (DE) | 2006-08-30 | — | — | EP | disclosed |
| US-6926943-B2 | Use of light-absorbing compounds in the information layer of optical data carriers, and optical data carriers | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-09 | — | — | US | disclosed |
| US-20030175616-A1 | Optical recording media; high density writing | LANXESS DEUTSCHLAND GMBH (DE) | 2003-09-18 | — | — | US | disclosed |
| EP-1273006-A1 | USE OF LIGHT-ABSORBING COMPOUNDS IN THE INFORMATION LAYER OF OPTICAL DATA CARRIERS, AND OPTICAL DATA CARRIERS | Bayer Aktiengesellschaft (DE) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001075873-A1 | USE OF LIGHT-ABSORBING COMPOUNDS IN THE INFORMATION LAYER OF OPTICAL DATA CARRIERS, AND OPTICAL DATA CARRIERS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-11 | — | — | WO | disclosed |