SCHEMBL348908

SCHEMBL348908

O=[C]N1CCCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3547528 1.00 CTSL (0.42)
SCHEMBL518260 1.00 CTSL (0.42)
SCHEMBL3542998 1.00 CTSL (0.42)
SCHEMBL2637 1.00
SCHEMBL3544433 1.00 CTSL (0.42)
SCHEMBL3548111 1.00 CTSL (0.42)
SCHEMBL7597 0.96
SCHEMBL8728 0.89
SCHEMBL209742 0.81
SCHEMBL1396359 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 753 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024114814-A1 JAK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS ONQUALITY PHARMACEUTICALS CHINA LTD (CN) 2024-06-06 WO claimed
US-20230046680-A1 NOVEL HETEROARYL-SUBSTITUTED AMINOALKYL AZOLE COMPOUNDS AS PESTICIDES ELANCO ANIMAL HEALTH GMBH (DE) 2023-02-16 US claimed
EP-3956325-A1 NOVEL HETEROARYL-SUBSTITUTED AMINOALKYL AZOLE COMPOUNDS AS PESTICIDES Bayer Animal Health GmbH (DE) 2022-02-23 EP claimed
WO-2020212235-A1 NOVEL HETEROARYL-SUBSTITUTED AMINOALKYL AZOLE COMPOUNDS AS PESTICIDES BAYER ANIMAL HEALTH GMBH (DE) 2020-10-22 WO claimed
EP-2949644-A2 SUBSTITUTED TETRACYCLINE COMPOUNDS Paratek Pharmaceuticals, Inc. (US) 2015-12-02 EP claimed
US-20140155357-A1 SUBSTITUTED TETRACYCLINE COMPOUNDS PARATEK PHARMACEUTICALS, INC. 2014-06-05 US claimed
EP-2069327-B1 NEW PYRIDONE DERIVATIVES WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS BOEHRINGER INGELHEIM INT (DE) 2013-10-16 EP claimed
EP-1558578-B1 NOVEL ALKYNE COMPOUNDS HAVING AN MCH ANTAGONISTIC EFFECT AND MEDICAMENTS CONTAINING THESE COMPOUNDS BOEHRINGER INGELHEIM PHARMA (DE) 2013-03-13 EP claimed
US-20120010185-A1 NEW PYRIDONE DERIVATES WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-01-12 US claimed
EP-1838709-B1 1,5,6-SUBSTITUTED-2-OXO-3-CYANO-1,6A-DIAZA-TETRAHYDRO-FLUORANTHENES AS ANTI-INFECTIVE AGENTS TIBOTEC PHARM LTD (IE) 2011-12-21 EP claimed
EP-0476515-A1 New amino acid derivatives, a process for the preparation thereof and pharmaceutical composition comprising the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-03-25 EP claimed
US-5025005-A Preventive or therapeutic agents for circulatory diseases, allergic disorders; antineoplastic agent; inhibitor for platelet activating factor TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-06-18 US claimed
EP-0173821-B1 SUBSTITUTED 5-AMINO-1-PHENYL PYRAZOLES BAYER AG (DE) 1989-01-18 EP claimed
US-4740232-A Substituted 5-amino-1-phenylpyrazoles composition containing them and herbicidal method of using them BAYER AKTIENGESELLSCHAFT (DE) 1988-04-26 US claimed
US-4737518-A ANTIALLERGENS, ANTINEOPLASTICS, ANTICOAGULANTS, CIRCULATORY DISEASES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-04-12 US claimed
US-4685956-A 1-aryl-5-hydrazino-pyrazoles, compositions containing them, and herbicidal method of using them BAYER AKTIENGESELLSCHAFT (DE) 1987-08-11 US claimed
EP-0212353-A2 1-Aryl-5-hydrazino-pyrazoles BAYER AG (DE) 1987-03-04 EP claimed
EP-0205021-A2 5-Amino-4-cyano-1-pyridyl pyrazoles BAYER AG (DE) 1986-12-17 EP claimed
EP-0001312-B1 NOVEL 1,2-DICHLOROCYANOVINYL SULFIDES, SULFOXIDES AND SULFONES, BIOCIDAL PREPARATIONS COMPRISING THEM, AS WELL AS A METHOD OF CONTROLLING MICROORGANISMS BY USING SAID COMPOUNDS OR PREPARATIONS STAUFFER CHEMICAL COMPANY (US) 1981-12-30 EP claimed
EP-0001312-A1 Novel 1,2-dichlorocyanovinyl sulfides, sulfoxides and sulfones, biocidal preparations comprising them, as well as a method of controlling microorganisms by using said compounds or preparations STAUFFER CHEMICAL COMPANY (US) 1979-04-04 EP claimed