Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.56 |
| ▸ | IP6K1 | Q92551 | 5/20 | 0.53 |
| ▸ | IP6K3 | Q96PC2 | 3/20 | 0.53 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28224558 | 0.91 | MAPKAPK2 (0.58) | MAPKAPK2IP6K1IP6K3IP6K2PIK3CD | |
| SCHEMBL13266887 | 0.84 | PIK3CD (0.59) | MAPKAPK2PIK3CDPIK3CAPIK3CBAURKA | |
| SCHEMBL29720511 | 0.81 | DRD4 (0.55) | MAPKAPK2PIK3CAJAK2PARP1HRH3 | |
| SCHEMBL13244673 | 0.80 | PIK3CD (0.55) | MAPKAPK2IP6K1IP6K3IP6K2PIK3CD | |
| SCHEMBL110226 | 0.79 | HRH3 (0.49) | MAPKAPK2JAK2MAPK1PARP1HRH3 | |
| SCHEMBL18643551 | 0.78 | PARP1 (0.54) | IP6K1KDRPARP1IDO1TDO2 | |
| SCHEMBL8871230 | 0.77 | PIK3CD (0.80) | IP6K1IP6K3IP6K2PIK3CDPIK3CA | |
| SCHEMBL349204 | 0.76 | CHEK1 (0.53) | MAPKAPK2MAPK1PARP1HRH3CHEK1 | |
| SCHEMBL27683290 | 0.76 | PARP1 (0.52) | AURKAPARP1CHEK1IDO1TDO2 | |
| SCHEMBL21524687 | 0.75 | PARP1 (0.51) | MAPKAPK2KDRPARP1CHEK1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107252429-B | Novel anti-inflammatory agent | 雷斯韦洛吉克斯公司 | 2023-06-16 | — | — | CN | disclosed |
| US-8889698-B2 | Compounds for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2014-11-18 | — | — | US | disclosed |
| CN-102458405-A | Novel anti-inflammatory agents | RESVERLOGIX CORP | 2012-05-16 | — | — | CN | disclosed |
| US-20120015905-A1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP. | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015905-A1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | APOB, HDLBP, FABP3 | MAPKAPK2 1842/4885IP6K1 1341/4885IP6K3 1671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.