Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.61 |
| ▸ | BRD2 | P25440 | 2/20 | 0.60 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.60 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.60 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.60 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.60 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.60 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.60 |
| ▸ | BRD1 | O95696 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349074 | 0.88 | BRD4 (0.65) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL30053021 | 0.88 | BRD4 (0.65) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL348712 | 0.86 | BRD4 (0.59) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL30433788 | 0.82 | BRD4 (0.66) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL120734 | 0.82 | BRD4 (0.66) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL30434465 | 0.79 | BRD4 (0.67) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL149248 | 0.79 | BRD4 (0.67) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL348695 | 0.78 | BRD4 (0.67) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL348978 | 0.78 | HDAC1 (0.69) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL377730 | 0.78 | BRD4 (0.58) | BRD4HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015905-A1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP. | 2012-01-19 | — | — | US | disclosed |
| US-8053440-B2 | Compounds for the prevention and treatment of cardiovascular diseases | Resverlogix Corporation (CA) | 2011-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015905-A1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | APOB, HDLBP, FABP3 | BRD4 1910/4885HDAC1 510/4885HDAC3 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.