Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.75 |
| ▸ | POLA1 | P09884 | 1/20 | 0.74 |
| ▸ | OSBP | P22059 | 4/20 | 0.71 |
| ▸ | RORC | P51449 | 3/20 | 0.71 |
| ▸ | USP2 | O75604 | 2/20 | 0.71 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.71 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.61 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.61 |
| ▸ | GBA1 | P04062 | 2/20 | 0.60 |
| ▸ | UGCG | Q16739 | 2/20 | 0.60 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.60 |
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.59 |
| ▸ | CRYAB | P02511 | 1/20 | 0.58 |
| ▸ | HMGCR | P04035 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGAV | P06756 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593421 | 1.00 | CYP46A1 (0.75) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL28895219 | 1.00 | CYP46A1 (0.75) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL27320611 | 1.00 | CYP46A1 (0.75) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL349479 | 1.00 | CYP46A1 (0.75) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL21879230 | 0.99 | CYP46A1 (0.74) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL15174782 | 0.99 | CYP46A1 (0.74) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL27762145 | 0.99 | CYP46A1 (0.74) | CYP46A1POLA1OSBPRORCUSP2 | |
| Dimethyl Sulfoxide SCHEMBL9614562 | 0.96 | CYP46A1 (0.70) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL14174362 | 0.94 | CYP46A1 (0.74) | CYP46A1POLA1OSBPRORCUSP2 | |
| SCHEMBL28419590 | 0.93 | CYP46A1 (0.71) | CYP46A1POLA1OSBPRORCUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 780 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326839-A1 | TREATMENT OF DISEASES RELATED TO COLONY-STIMULATING FACTOR 1 RECEPTOR DYSFUNCTION USING TREM2 AGONISTS | VIGIL NEUROSCIENCE INC (US) | 2025-10-23 | — | — | US | claimed |
| US-20250282866-A1 | TREATMENT OF DISEASES RELATED TO ATP-BINDING CASSETTE TRANSPORTER 1 DYSFUNCTION USING TREM2 AGONISTS | VIGIL NEUROSCIENCE INC (US) | 2025-09-11 | — | — | US | claimed |
| CN-119654146-A | Composition for caring keratin materials and dressing film comprising same | 莱雅公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119638601-A | Guanidine-derived ionizable lipid material, preparation method and application | 中国海洋大学 | 2025-03-18 | — | — | CN | claimed |
| US-20240261254-A1 | DIHYDROMYRICETIN NANOEMULSION FORMULATIONS AND METHODS FOR FORMING THEM | CHEERS HEALTH, INC. (US) | 2024-08-08 | — | — | US | claimed |
| CN-117015400-A | Treatment of diseases associated with ATP-binding cassette transporter 1 dysfunction using TREM2 agonists | 维吉尔神经科学股份有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116964454-A | Treatment of diseases associated with colony stimulating factor 1 receptor dysfunction using TREM2 agonists | 维吉尔神经科学股份有限公司 | 2023-10-27 | — | — | CN | claimed |
| EP-4255567-A1 | TREATMENT OF DISEASES RELATED TO ATP-BINDING CASSETTE TRANSPORTER 1 DYSFUNCTION USING TREM2 AGONISTS | Vigil Neuroscience, Inc. (US) | 2023-10-11 | — | — | EP | claimed |
| CN-112641757-B | Carrier for transmembrane delivery of molecules and preparation method thereof | 中国药科大学 | 2023-07-28 | — | — | CN | claimed |
| EP-4192881-A2 | TREATMENT OF DISEASES RELATED TO COLONY-STIMULATING FACTOR 1 RECEPTOR DYSFUNCTION USING TREM2 AGONISTS | Vigil Neuroscience, Inc. (US) | 2023-06-14 | — | — | EP | claimed |
| WO-1994021230-A1 | METHOD AND COMPOSITIONS FOR DISRUPTING THE EPITHELIAL BARRIER FUNCTION | CELLEGY PHARMACEUTICALS, INC. (US) | 1994-09-29 | — | — | WO | claimed |
| EP-0582503-A1 | Composition formed of an aqueous dispersion of stabilized vesicles of amphiphilic non-ionic lipids | L'OREAL (FR) | 1994-02-09 | — | — | EP | claimed |
| US-5277914-A | Encapsulation in non-halogenated aprotic solvent | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-01-11 | — | — | US | claimed |
| EP-0544874-A1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | L'OREAL (FR) | 1993-06-09 | — | — | EP | claimed |
| WO-1993000068-A1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | L'OREAL (FR) | 1993-01-07 | — | — | WO | claimed |
| EP-0467954-A4 | PREPARATION OF LIPOSOME AND LIPID COMPLEX COMPOSITIONS | — | 1992-06-03 | — | — | EP | claimed |
| EP-0467954-A1 | PREPARATION OF LIPOSOME AND LIPID COMPLEX COMPOSITIONS. | UNIV CALIFORNIA (US) | 1992-01-29 | — | — | EP | claimed |
| US-5077057-A | Dissolving in aprotic solvent; extrusion into aqueous solution | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-12-31 | — | — | US | claimed |
| WO-1990011780-A1 | PREPARATION OF LIPOSOME AND LIPID COMPLEX COMPOSITIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1990-10-18 | — | — | WO | claimed |
| WO-1990006775-A1 | A NOVEL NONPHOSPHOLIPID LIPOSOME COMPOSITION FOR SUSTAINED RELEASE OF DRUGS | LIPOSOME TECHNOLOGY, INC. (US) | 1990-06-28 | — | — | WO | claimed |