Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.45 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.45 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.45 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.45 |
| ▸ | GAPDH | P04406 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061066 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL26801670 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL2493929 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL2493931 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL5707687 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL14274463 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL11726595 | 1.00 | USP2 (0.55) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL3272584 | 0.99 | USP2 (0.54) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL6022376 | 0.99 | USP2 (0.54) | USP2POLBMEN1KMT2APTPN1 | |
| SCHEMBL3663518 | 0.99 | USP2 (0.54) | USP2POLBMEN1KMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |
| US-20100210833-A1 | METHOD OF PRODUCING NUCLEOSIDES | CILAG AG (CH) | 2010-08-19 | — | — | US | disclosed |
| EP-2197892-A2 | METHOD OF PRODUCING NUCLEOSIDES | Cilag AG (CH) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009047314-A2 | METHOD OF PRODUCING NUCLEOSIDES | CILAG AG (CH) | 2009-04-16 | — | — | WO | disclosed |
| US-20060229275-A1 | Production method of 2-deoxy-L-ribofuranosyl chloride compound | AJINOMOTO CO. INC (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1705181-A2 | Production method of 2-deoxy-L-ribofuranosyl chloride compound | AJINOMOTO CO., INC. (JP) | 2006-09-27 | — | — | EP | disclosed |
| US-20060094031-A1 | Alpha-L-arabinofuranosidase histochemical reporter gene assay | STOWERS INSTITUTE FOR MEDICAL RESEARCH | 2006-05-04 | — | — | US | disclosed |
| JP-2000186098-A | PRODUCTION OF A-76202 AND ITS ANALOGOUS COMPOUND | SANKYO CO LTD | 2000-07-04 | — | — | JP | disclosed |
| EP-0063481-B1 | WATER-SOLUBLE ANTITUMOR, ANTIVIRAL AND IMMUNOSUPPRESSANT COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-10-17 | — | — | EP | disclosed |
| US-4464531-A | ANTITUMOR AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-07 | — | — | US | disclosed |
| EP-0063481-A1 | Water-soluble antitumor, antiviral and immunosuppressant compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094031-A1 | Alpha-L-arabinofuranosidase histochemical reporter gene assay | GUSB, FUCA1, ENGASE | USP2 1246/4885POLB 2560/4885MEN1 4693/4885 |
| US-20060229275-A1 | Production method of 2-deoxy-L-ribofuranosyl chloride compound | DCTD, DERA, HDHD5 | USP2 1312/4885POLB 955/4885MEN1 4773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.