Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.41 |
| ▸ | CTSK | P43235 | 16/20 | 0.38 |
| ▸ | CTSL | P07711 | 4/20 | 0.34 |
| ▸ | CTSB | P07858 | 4/20 | 0.34 |
| ▸ | CTSH | P09668 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19744852 | 0.78 | CTSK (0.38) | FOLH1CTSKCTSLCTSBCTSH | |
| SCHEMBL14542293 | 0.78 | CTSK (0.38) | FOLH1CTSKCTSLCTSBCTSH | |
| SCHEMBL4820406 | 0.77 | CTSK (0.60) | CTSKCTSLCTSBCTSH | |
| SCHEMBL4820415 | 0.77 | CTSK (0.60) | CTSKCTSLCTSBCTSH | |
| SCHEMBL6402771 | 0.75 | CTSK (0.44) | CTSKCTSLCTSBCTSH | |
| SCHEMBL4907367 | 0.74 | CTSK (0.57) | CTSKCTSLCTSBCTSH | |
| SCHEMBL4786392 | 0.72 | CTSK (0.50) | CTSKCTSLCTSBCTSH | |
| SCHEMBL328961 | 0.72 | CTSK (0.50) | CTSKCTSLCTSBCTSH | |
| SCHEMBL9577815 | 0.72 | CTSK (0.35) | CTSKCTSLCTSBCTSH | |
| SCHEMBL9249954 | 0.71 | FOLH1 (0.41) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100136024-A1 | Selective Inhibition of Histone Deacetylase 6 for Ocular Neuroprotection or for Treatment or Control of Glaucoma | BAUSCH & LOMB INCORPORATED | 2010-06-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100136024-A1 | Selective Inhibition of Histone Deacetylase 6 for Ocular Neuroprotection or for Treatment or Control of Glaucoma | HDAC6, HDAC1, HDAC7 | FOLH1 1932/4885CTSK 758/4885CTSL 2982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.